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World J Gastroenterol. Dec 28, 2018; 24(48): 5433-5438
Published online Dec 28, 2018. doi: 10.3748/wjg.v24.i48.5433
Checkpoint inhibitors: What gastroenterologists need to know
Monjur Ahmed
Monjur Ahmed, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Thomas Jefferson University, Philadelphia, PA 19107, United States
Author contributions: Ahmed M finished this manuscript alone.
Conflict-of-interest statement: No conflict of interest exists.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Monjur Ahmed, MD, FRCP, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Thomas Jefferson University, 132 South 10th Street, Suite 468, Main Building, Philadelphia, PA 19107, United States. monjur.ahmed@jefferson.edu.
Telephone: +1-215-9521493 Fax: +1-215-7551850
Received: September 28, 2018
Peer-review started: September 28, 2018
First decision: October 26, 2018
Revised: November 7, 2018
Accepted: November 16, 2018
Article in press: November 16, 2018
Published online: December 28, 2018
Processing time: 90 Days and 12.4 Hours
Core Tip

Core tip: Checkpoint inhibitors are a kind of immunotherapy used in the treatment of various malignancies. Nevertheless, they carry the risk of causing different immune-related side effects. Physicians should be vigilant in recognizing and appropriately managing these side effects for a better outcome.