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Copyright ©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. May 14, 2018; 24(18): 2024-2035
Published online May 14, 2018. doi: 10.3748/wjg.v24.i18.2024
Quantitative assessment of hepatic fibrosis in chronic hepatitis B and C: T1 mapping on Gd-EOB-DTPA-enhanced liver magnetic resonance imaging
Shen Pan, Xiao-Qi Wang, Qi-Yong Guo
Shen Pan, Qi-Yong Guo, Department of Radiology, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning Province, China
Xiao-Qi Wang, Department of Clinical Science, Philips Healthcare, Beijing 100600, China
Author contributions: Pan S and Wang XQ contributed to this work; Pan S and Guo QY designed research; and Pan S wrote the paper.
Supported by National Natural Science Foundation of China, No. 81771893, No. 81771802, No. 81471718 and No. 81401376; and Outstanding Youth Foundation of China Medical University, No. YQ20160005.
Institutional review board statement: This study was reviewed and approved by the Shengjing Hospital of China Medical University Institution Review Board, ID# 2014PS103K.
Informed consent statement: The authors of this paper guarantee that all study participants or their legal guardian(s) provided informed written consent about personal and medical data collection prior to study enrolment.
Conflict-of-interest statement: There are no conflict of interests in relation to this manuscript.
Data sharing statement: There are no additional data available in relation to this manuscript.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Qi-Yong Guo, MD, Professor, Department of Radiology, Shengjing Hospital of China Medical University, No. 36 Sanhao Street, Heping District, Shenyang 110004, Liaoning Province, China. guoqysj@126.com
Telephone: +86-13840231345 Fax: +86-96615-73219
Received: March 9, 2018
Peer-review started: March 9, 2018
First decision: March 29, 2018
Revised: April 6, 2018
Accepted: April 15, 2018
Article in press: April 15, 2018
Published online: May 14, 2018
Processing time: 63 Days and 3.4 Hours
Core Tip

Core tip: T1 mapping using the Look-Locker method with gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid-enhanced magnetic resonance imaging at 3-Tesla by calculating the hepatocyte fraction is an efficient method for the assessment of liver fibrosis in patients with chronic hepatitis B and C, and this method is superior to using reduction rate.