Randomized Clinical Trial
Copyright ©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Apr 28, 2018; 24(16): 1803-1811
Published online Apr 28, 2018. doi: 10.3748/wjg.v24.i16.1803
Papillary fistulotomy vs conventional cannulation for endoscopic biliary access: A prospective randomized trial
Carlos Kiyoshi Furuya, Paulo Sakai, Fabio Ramalho Tavares Marinho, Jose Pinhata Otoch, Spencer Cheng, Lívia Lemes Prudencio, Eduardo Guimarães Hourneaux de Moura, Everson Luiz de Almeida Artifon
Carlos Kiyoshi Furuya, Paulo Sakai, Fabio Ramalho Tavares Marinho, Spencer Cheng, Eduardo Guimarães Hourneaux de Moura, Department of Gastrointestinal Endoscopy Unit, University of Sao Paulo, Sao Paulo 05409001, Brazil
Jose Pinhata Otoch, Lívia Lemes Prudencio, Department of Surgery, University of Sao Paulo, Sao Paulo 05403000, Brazil
Everson Luiz de Almeida Artifon, Department of Gastroenterology and Radiology, University of Sao Paulo, Sao Paulo 04107-030, Brazil
Author contributions: Furuya CK designed and performed the research; Sakai P, Marinho FRT and Prudencio LL wrote the paper; Otoch JP and de Moura EGH analyzed the data; Artifon EL performed the research and analyzed the data.
Institutional review board statement: The study was reviewed and approved by Ethics Committee for Research Project Analysis of Clinics Hospital, University of Sao Paulo and UNILUS Ethics Subcommittee.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All authors declare no potential conflicting interests related to this paper.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Carlos Kiyoshi Furuya, MD, PhD, Medical Assistant, Department of Gastrointestinal Endoscopy Unit, University of Sao Paulo, Av. Dr. Eneas de Carvalho Aguiar, 255 Predio dos Ambulatorios-6 andar-Bloco 3, Sao Paulo 5409001, Brazil. carloskfjr@gmail.com
Telephone: +55-11-30697579
Received: February 25, 2018
Peer-review started: February 26, 2018
First decision: March 9, 2018
Revised: March 12, 2018
Accepted: March 25, 2018
Article in press: March 25, 2018
Published online: April 28, 2018
Processing time: 60 Days and 4.1 Hours
Core Tip

Core tip: Biliary cannulation is the first step of therapeutic endoscopic retrograde cholangiopancreatography and can determine several complications. There are small numbers of papers regarding comparison between conventional cannulation vs fistulotomy. Our study is a well-designed approach in its matter. In fact, we compare the cannulation success, biochemical profile and complications of the papillary fistulotomy technique versus catheter and guidewire standard access. Papillary fistulotomy was more effective than guidewire cannulation, and it was associated with a lower profile of amylase and lipase, as the routine endoscopic access to the biliary tree, including difficult cases. Complications were similar in both groups.