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©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Feb 21, 2017; 23(7): 1262-1267
Published online Feb 21, 2017. doi: 10.3748/wjg.v23.i7.1262
Published online Feb 21, 2017. doi: 10.3748/wjg.v23.i7.1262
Predictors of poor outcomes in patients with wild mushroom-induced acute liver injury
Taerim Kim, Jae Ho Lee, Yoon-Seon Lee, Bum Jin Oh, Kyoung Soo Lim, Won Young Kim, Department of Emergency Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul 05505, South Korea
Danbi Lee, Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, South Korea
Author contributions: Lee JH, Lee YS, Oh BJ, Lim KS and Kim WY designed the research; Lee D performed the research; Kim T collected data; Kim WY analyzed data; Kim T and Kim WY wrote the paper; all authors have read and approved the final version to be published.
Institutional review board statement: Based on the Declaration of Helsinki, Asan Medical Center Institutional Review Board approved the retrospective use of the clinical, biochemical, and radiographic data for the present study.
Informed consent statement: The requirements for informed consent were waived due to the retrospective design.
Conflict-of-interest statement: The authors declare they have no potential conflicts of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Won Young Kim, MD, PhD, Department of Emergency Medicine, University of Ulsan College of Medicine, Asan Medical Center, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, South Korea. wonpia73@naver.com
Telephone: +82-2-30103350 Fax: +82-2-30103360
Received: November 7, 2016
Peer-review started: November 7, 2016
First decision: December 19, 2016
Revised: January 2, 2017
Accepted: January 11, 2017
Article in press: January 11, 2017
Published online: February 21, 2017
Processing time: 105 Days and 8.7 Hours
Peer-review started: November 7, 2016
First decision: December 19, 2016
Revised: January 2, 2017
Accepted: January 11, 2017
Article in press: January 11, 2017
Published online: February 21, 2017
Processing time: 105 Days and 8.7 Hours
Core Tip
Core tip: Wild mushroom-induced acute liver failure is potentially fatal. Many candidates for liver transplantation progress to multi-organ failure resulting in deterioration while awaiting liver transplantation. Identifying early predictive markers of poor outcomes in patients with acute liver injury resulting from wild mushroom intoxication is critical for improving survival rates. Total bilirubin and activated partial thromboplastin time (aPTT) levels were associated with in-hospital mortality in patients with acute liver injury from wild mushroom intoxication. Monitoring total bilirubin and aPTT as predictors of survival outcomes may determines the need for advanced intervention such as liver transplantation.