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©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Oct 28, 2017; 23(40): 7332-7336
Published online Oct 28, 2017. doi: 10.3748/wjg.v23.i40.7332
Published online Oct 28, 2017. doi: 10.3748/wjg.v23.i40.7332
Case of familial hyperlipoproteinemia type III hypertriglyceridemia induced acute pancreatitis: Role for outpatient apheresis maintenance therapy
Mohannad Abou Saleh, Emad Mansoor, Department of Internal Medicine, University Hospitals Cleveland Medical Center, Case Western Reserve University, Cleveland, OH 44106, United States
Gregory S Cooper, Division of Gastroenterology and Liver Disease, Department of Internal Medicine, University Hospitals Cleveland Medical Center, Case Western Reserve University, Cleveland, OH 44106, United States
Author contributions: Abou Saleh M, Mansoor E and Cooper GS have all designed the case report, analyzed data, and written the manuscript.
Institutional review board statement: This case report was exempt from the Institutional Review Board standards at Case Western Reserve University/University Hospitals Cleveland Medical Center.
Informed consent statement: The patient involved in this study gave his written informed consent authorizing use and disclosure of his protected health information.
Conflict-of-interest statement: There are no potential conflicts (financial, professional, or personal) to disclose by all the authors.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Gregory S Cooper, MD, Division of Gastroenterology and Liver Disease, Department of Internal Medicine, University Hospitals Cleveland Medical Center, Case Western Reserve University, 11100 Euclid Avenue, Cleveland, OH 44106, United States. gregory.cooper@uhhospitals.org
Telephone: +1-216-8445385 Fax: +1-216-8445385
Received: May 30, 2017
Peer-review started: June 3, 2017
First decision: June 22, 2017
Revised: July 10, 2017
Accepted: August 1, 2017
Article in press: August 2, 2017
Published online: October 28, 2017
Processing time: 151 Days and 14.3 Hours
Peer-review started: June 3, 2017
First decision: June 22, 2017
Revised: July 10, 2017
Accepted: August 1, 2017
Article in press: August 2, 2017
Published online: October 28, 2017
Processing time: 151 Days and 14.3 Hours
Core Tip
Core tip: There are a number of retrospective studies that have suggested a role for apheresis and insulin infusion in the acute management of hypertriglyceridemic pancreatitis (HTGP) but the post-discharge course and outpatient management of HTGP remain unclear. We report a case of HTGP in a male with hyperlipoproteinemia type III who was treated successfully with insulin and apheresis on the initial inpatient presentation followed by bi-monthly outpatient maintenance apheresis sessions for the prevention of recurrent HTGP. We also reviewed the literature for the different inpatient and outpatient management modalities of HTGP.