Lin JZ, Long JY, Wang AQ, Zheng Y, Zhao HT. Precision medicine: In need of guidance and surveillance. World J Gastroenterol 2017; 23(28): 5045-5050 [PMID: 28811702 DOI: 10.3748/wjg.v23.i28.5045]
Corresponding Author of This Article
Hai-Tao Zhao, MD, PhD, Professor, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 9 Dongdansantiao, Dongcheng District, Beijing 100730, China. zhaoht@pumch.cn
Research Domain of This Article
Medicine, General & Internal
Article-Type of This Article
Editorial
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Jian-Zhen Lin, Jun-Yu Long, An-Qiang Wang, Hai-Tao Zhao, Department of Liver Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China
Ying Zheng, State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Science, University of Macau, Macau SAR, China
Author contributions: Lin JZ wrote the manuscript; Long JY, Wang AQ and Zheng Y contributed to the intellectual content; Zhao HT revised and modified the manuscript.
Supported byInternational Science and Technology Cooperation Projects, No. 2016YFE0107100, No. 2015DFA30650 and No. 2010DFB33720; Capital Special Research Project for Health Development, No. 2014-2-4012; Capital Research Project for The Characteristics Clinical Application No. Z151100004015170; Beijing Nature Science Foundation for Young Scholars Project, No. 7164293; and Program for New Century Excellent Talents in University, No. NCET-11-0288.
Conflict-of-interest statement: All the authors declare no conflict of interest related to this publication and approve the final version of the manuscript.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Hai-Tao Zhao, MD, PhD, Professor, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 9 Dongdansantiao, Dongcheng District, Beijing 100730, China. zhaoht@pumch.cn
Telephone: +86-10-69156042 Fax: +86-10-69156043
Received: March 22, 2017 Peer-review started: March 23, 2017 First decision: April 10, 2017 Revised: April 15, 2017 Accepted: June 1, 2017 Article in press: June 1, 2017 Published online: July 28, 2017 Processing time: 127 Days and 18.5 Hours
Core Tip
Core tip: Precision medicine aims toward accurate, efficient and effective diagnostic testing and precise treatment. Emerging techniques and therapeutic drugs based on molecular profiling and genomic characteristics will help achieve that goal. Next-generation sequencing is the most frequently used methodology for precision medicine applications; however, proteomics and metabolomics tests are growing in accuracy and ease of use. In terms of applications and outcomes, the benefits conferred by precision medicine are currently insufficient. Present development of precision medicine lacks order. Therefore, precision medicine needs strong support to develop, and a directed momentum is required. We suggest three kinds of impetus (research, application and collaboration impetus) for such directed momentum toward promoting precision medicine and accelerating its clinical translation and application.
