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©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jul 14, 2017; 23(26): 4823-4830
Published online Jul 14, 2017. doi: 10.3748/wjg.v23.i26.4823
Published online Jul 14, 2017. doi: 10.3748/wjg.v23.i26.4823
Predictive factors for body weight loss and its impact on quality of life following gastrectomy
Kazuaki Tanabe, Department of Gastroenterological Surgery, Hiroshima University Hospital, Hiroshima 734-8551, Japan
Masazumi Takahashi, Division of Gastroenterological Surgery, Yokohama Municipal Citizen’s Hospital, Yokohama 240-8555, Japan
Takashi Urushihara, Department of Gastroenterological, Breast and Transplant Surgery, Hiroshima Prefectural Hospital, Hiroshima 734-8530, Japan
Yoichi Nakamura, Department of Surgery, Toho University Ohashi Medical Center, Tokyo 153-8515, Japan
Makoto Yamada, Department of Surgery, Gifu Municipal Hospital, Gifu 500-8513, Japan
Sang-Woong Lee, Department of General and Gastroenterological Surgery, Osaka Medical College, Takatsuki 569-8686, Japan
Shinnosuke Tanaka, Department of Gastroenterological Surgery, Fukuoka University School of Medicine, Fukuoka 814-0180, Japan
Akira Miki, Department of Surgery, Kobe City Medical Center General Hospital, Kobe 650-0047, Japan
Masami Ikeda, Department of Surgery, Asama General Hospital, Saku 385-8558, Japan
Koji Nakada, Department of Laboratory Medicine, the Jikei University School of Medicine, Tokyo 105-8471, Japan
Author contributions: Tanabe K, Takahashi M, Urushihara T, Nakamura Y, Yamada M, Lee SW, Tanaka S, Miki A, Ikeda M and Nakada K collected data; Nakada K managed the study; Tanabe K wrote the paper; all authors have read and approved the final version to be published.
Supported by Jikei University School of Medicine and the Japanese Society for Gastro-surgical Pathophysiology ; JPGSWP and registered to UMIN-CTR #000002116 entitled .
Institutional review board statement: This study was approved by the local ethics committees at each participating institution.
Informed consent statement: Written informed consent was obtained from all enrolled patients.
Conflict-of-interest statement: The authors declare no conflicts of interest related to the publication of this study.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Dr. Kazuaki Tanabe, Department of Gastroenterological Surgery, Hiroshima University Hospital, 1-2-3, Kasumi, Minami-ku, Hiroshima 734-8551, Japan. ktanabe2@hiroshima-u.ac.jp
Telephone: +81-82-2575222 Fax: +81-82-2575224
Received: February 11, 2017
Peer-review started: February 14, 2017
First decision: March 16, 2017
Revised: April 3, 2017
Accepted: May 4, 2017
Article in press: May 4, 2017
Published online: July 14, 2017
Processing time: 150 Days and 17.7 Hours
Peer-review started: February 14, 2017
First decision: March 16, 2017
Revised: April 3, 2017
Accepted: May 4, 2017
Article in press: May 4, 2017
Published online: July 14, 2017
Processing time: 150 Days and 17.7 Hours
Core Tip
Core tip: Our study of almost 1800 gastrectomy patients revealed that higher preoperative body mass index, total gastrectomy, and female sex were independent predictors of greater body weight loss after gastrectomy. Moreover, we determined lower postoperative body mass index, rather than greater postoperative weight loss, as a certain factor of worse quality of life (QOL), although the effect was not substantial. We believe that this contribution is theoretically and practically relevant in the current context of gastric cancer treatment and recovery because early diagnosis and improved treatments have led to increased long-term survival postgastrectomy, highlighting the need for better QOL.