Observational Study
Copyright ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jul 7, 2017; 23(25): 4615-4623
Published online Jul 7, 2017. doi: 10.3748/wjg.v23.i25.4615
Cryptogenic multifocal ulcerous stenosing enteritis: Radiologic features and clinical behavior
Jiyoung Hwang, Jin Sil Kim, Ah Young Kim, Joon Seok Lim, Se Hyung Kim, Min Ju Kim, Mi Sung Kim, Kyoung Doo Song, Ji Young Woo
Jiyoung Hwang, Department of Radiology, Soonchunhyang University Seoul Hospital, Seoul 04401, South Korea
Jin Sil Kim, Ah Young Kim, Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul 05505, South Korea
Joon Seok Lim, Department of Radiology, Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul 03722, South Korea
Se Hyung Kim, Department of Radiology, Seoul National University Hospital, Seoul 03080, South Korea
Min Ju Kim, Department of Radiology, Anam Hospital, Korea University College of Medicine, Seoul 15355, South Korea
Mi Sung Kim, Department of Radiology, Sungkyunkwan University School of Medicine, Kangbuk Samsung Hospital, Seoul 03181, South Korea
Kyoung Doo Song, Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, South Korea
Ji Young Woo, Department of Radiology, Hallym University College of Medicine, Kangnam Sacred Heart Hospital, Seoul 07441, South Korea
Author contributions: Hwang J and Kim JS contributed equally to this work; Kim AY, Lim JS, Kim SH, Kim MJ, Kim MS, Song KD and Woo JY collected the data; Kim AY managed the study; Hwang J, Kim JS and Kim AY contributed to the analysis and wrote the paper; all authors have read and approved the final version to be published.
Institutional review board statement: This study was approved by the institutional review board of Asan medical center, Seoul, South Korea (number, 2016-0235).
Conflict-of-interest statement: The authors declare no conflicts of interests related to the publication of this study.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Ah Young Kim, MD, PhD, Professor, Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, 88, Olympic-ro 43-gil, Songpa-gu, Seoul 05505, South Korea. aykim@amc.seoul.kr
Telephone: +82-2-30104361 Fax: +82-2-4764719
Received: February 15, 2017
Peer-review started: February 19, 2017
First decision: March 16, 2017
Revised: March 23, 2017
Accepted: May 19, 2017
Article in press: May 19, 2017
Published online: July 7, 2017
Processing time: 141 Days and 22.8 Hours
Core Tip

Core tip: The patients with multiple unexplained strictures and recurrent abdominal pain are challenging to most physician in daily practice. Because cryptogenic multifocal ulcerous stenosing enteritis (CMUSE) is a rare disease, this disease entity is frequently misdiagnosed as other small bowel diseases and often undergoes unnecessary surgery. Then, we focused on the characteristic radiologic and clinical findings of CMUSE that can differentiate the disease from other similar bowel diseases. In our study, characteristic radiologic features of CMUSE were multiple short strictures and/or shallow ulcers of the small intestine without significant bowel obstruction. Some strictures had recurrent shallow ulceration that might progress to more severe strictures. Under these radiologic findings with relapsing episodes, CMUSE should be considered when assessing patient with recurrent abdominal pain and anemia.