Retrospective Study
Copyright ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jul 7, 2017; 23(25): 4587-4594
Published online Jul 7, 2017. doi: 10.3748/wjg.v23.i25.4587
Chronic hepatitis B, nonalcoholic steatohepatitis and physical fitness of military males: CHIEF study
Yu-Jung Chen, Kai-Wen Chen, Yu-Leung Shih, Fang-Ying Su, Yen-Po Lin, Fan-Chun Meng, Felicia Lin, Yun-Shun Yu, Chih-Lu Han, Chih-Hung Wang, Jia-Wei Lin, Tsai-Yuan Hsieh, Yi-Hwei Li, Gen-Min Lin
Yu-Jung Chen, Kai-Wen Chen, Fan-Chun Meng, Felicia Lin, Yun-Shun Yu, Chih-Hung Wang, Gen-Min Lin, Department of Medicine, Hualien-Armed Forces General Hospital, Hualien 970, Taiwan
Yu-Jung Chen, Fang-Ying Su, Yi-Hwei Li, Institute of Medical Sciences and Department of Public Health, Tzu-Chi University, Hualien 970, Taiwan
Kai-Wen Chen, Yu-Leung Shih, Fan-Chun Meng, Chih-Hung Wang, Tsai-Yuan Hsieh, Gen-Min Lin, Departments of Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan
Yen-Po Lin, Department of Critical Care Medicine, Yonghe Cardinal Tien Hospital, New Taipei 234, Taiwan
Chih-Lu Han, Department of Medicine, Taipei Veterans General Hospital, Taipei 112, Taiwan
Jia-Wei Lin, Department of Dentistry, National Yang-Ming University, Taipei 112, Taiwan
Gen-Min Lin, Department of Electrical Engineering, National Dong Hwa University, Hualien 974, Taiwan
Author contributions: Li YH and Lin GM contributed equally to conception and design of the study, and acquisition and interpretation of the data; Su FY and Li YH analyzed the data; and Chen YJ drafted the article; all authors made critical revisions related to important intellectual content of the article and provided approval of the final version of the article to be published.
Supported by research grants from the Hualien-Armed Forces General Hospital, No. 805-C105-10; and the Ministry of National Defense-Medical Affairs Bureau, No. MAB-106-124.
Institutional review board statement: This study was reviewed and approved by the Institutional Review Board of Mennonite Christian Hospital in Taiwan.
Informed consent statement: Participants were not required to give informed consent to this retrospective study since the analysis of baseline characteristics used anonymized clinical data that were obtained after each patient had agreed to share the results by written informed consent.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Gen-Min Lin, MD, Department of Medicine, Hualien-Armed Forces General Hospital, No. 100, Jin-Feng Street, Hualien 970, Taiwan. farmer507@yahoo.com.tw
Telephone: +886-3-8260601 Fax: +886-3-8261370
Received: January 19, 2017
Peer-review started: January 22, 2017
First decision: March 16, 2014
Revised: March 24, 2014
Accepted: June 19, 2017
Article in press: June 19, 2017
Published online: July 7, 2017
Processing time: 168 Days and 13.5 Hours
Core Tip

Core tip: We investigated the association of chronic hepatitis B and nonalcoholic steatohepatitis with physical fitness in a large population of young adult Taiwanese military males. The results demonstrated that men with chronic hepatitis B had fewer 2-min push-up numbers than unaffected men, whereas men with nonalcoholic steatohepatitis had longer time to complete a 3000-m run and fewer 2-min sit-up numbers than unaffected men. Our findings suggest that chronic hepatitis B and nonalcoholic steatohepatitis might influence different physical performances. The mechanisms underlying the relationship between hepatitis and physical fitness are not fully understood and further investigations are needed.