Observational Study
Copyright ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jun 14, 2017; 23(22): 4080-4089
Published online Jun 14, 2017. doi: 10.3748/wjg.v23.i22.4080
Observation of the effect of targeted therapy of 64-slice spiral CT combined with cryoablation for liver cancer
Qiao-Huan Yan, Dian-Guo Xu, Yan-Feng Shen, Ding-Ling Yuan, Jun-Hui Bao, Hai-Bin Li, Ying-Gang Lv
Qiao-Huan Yan, Department of Geriatrics, the First Hospital of Handan, Handan 056001, Hebei Province, China
Dian-Guo Xu, Department of Anatomy, Medical College of Hebei University of Engineering, Handan 056001, Hebei Province, China
Yan-Feng Shen, Hai-Bin Li, Department of Oncology, Affiliated Hospital of Hebei University of Engineering, Handan 056001, Hebei Province, China
Ding-Ling Yuan, Jun-Hui Bao, Ying-Gang Lv, Department of Imaging, Affiliated Hospital of Hebei Medical University, Shijiazhuang 056002, Hebei Province, China
Ying-Gang Lv, Department of Radiology, Affiliated Hospital of Hebei University of Engineering, Handan 056001, Hebei Province, China
Author contributions: Yan QH and Lv YG contributed equally to this work; Yan QH, Xu DG, Shen YF, Yuan DL, Bao JH, Li HB and Lv YG designed research; Yan QH, Yuan DL, Bao JH, Li HB and Lv YG performed research; Yan QH, Xu DG, Shen YF, Li HB and Lv YG contributed new reagents/analytic tools; Yan QH, Xu DG, Shen YF and Lv YG analyzed data; and Yan QH and Lv YG wrote the paper.
Supported by Hebei Province Health Department of Scientific Research Fund Project, No. 20110157.
Institutional review board statement: The study was reviewed and approved by the Affiliated Hospital of Hebei University of Engineering Institutional Review Board.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors have no conflict of interest related to the manuscript.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Ying-Gang Lv, Deputy Chief Physician, Department of Radiology, Affiliated Hospital of Hebei University of Engineering, Jianshe Street No. 80, Fuxing District, Handan 056001, Hebei Province, China. lvyinggang@126.com
Telephone: +86-310-8577555 Fax: +86-310-8577555
Received: December 10, 2016
Peer-review started: December 12, 2016
First decision: December 29, 2016
Revised: February 15, 2017
Accepted: March 4, 2017
Article in press: March 4, 2017
Published online: June 14, 2017
Processing time: 185 Days and 15.1 Hours
Core Tip

Core tip: One hundred and twenty-four patients with liver cancer were accepted therapy by argon-helium superconducting surgery system. Compared with 64-row group, guided scan times was longer and freezing effective rate for tumors < 3 cm was lower in the dual-slice group. Four weeks after treatment, compared with dual-slice group, the hepatic artery perfusion and hepatic arterial perfusion index of tumor tissues were lower, the treatment effect and therapeutic efficacy in the 64-row group were higher. Complications were higher in the double-row group than in the 64-row group. 64-slice spiral computed tomography applied with cryoablation in targeted therapy for liver cancer can achieve a safe and effective freezing treatment.