Case Report
Copyright ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jun 7, 2017; 23(21): 3928-3933
Published online Jun 7, 2017. doi: 10.3748/wjg.v23.i21.3928
Esophageal carcinoma originating in the surface epithelium with immunohistochemically proven esophageal gland duct differentiation: A case report
Hiromi Tamura, Hirotsugu Saiki, Takahiro Amano, Masashi Yamamoto, Shiro Hayashi, Hiroka Ando, Reiko Doi, Tsutomu Nishida, Katsumi Yamamoto, Shiro Adachi
Hiromi Tamura, Hiroka Ando, Reiko Doi, Shiro Adachi, Department of Pathology, City Hospital of Toyonaka, Osaka 560-8565, Japan
Takahiro Amano, Masashi Yamamoto, Shiro Hayashi, Tsutomu Nishida, Department of Gastroenterology, City Hospital of Toyonaka, Osaka 560-8565, Japan
Hirotsugu Saiki, Katsumi Yamamoto, Department of Gastroenterology, JCHO Osaka Hospital, Osaka 553-0003, Japan
Author contributions: Tamura H wrote the manuscript; Ando H and Doi R contributed equally to this work by discussing the immunohistochemical data and histological diagnosis; Saiki H, Amano T, Yamamoto M, Hayashi S, Nishida T and Yamamoto K assessed the patients; Adachi S critically reviewed the manuscript.
Informed consent statement: Informed consent was obtained from the patient.
Conflict-of-interest statement: We have no conflict of interest in reporting the present case.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Hiromi Tamura, MD, Clinical Fellow, Department of Pathology, City Hospital of Toyonaka, Shibahara-cho 4-14-1, Toyonaka, Osaka 560-8565, Japan. watanabehiromi1107@hotmail.com
Telephone: +81-6-68430101 Fax: +81-6-68583531
Received: January 10, 2017
Peer-review started: January 12, 2017
First decision: March 3, 2017
Revised: March 17, 2017
Accepted: April 12, 2017
Article in press: April 12, 2017
Published online: June 7, 2017
Processing time: 147 Days and 15.8 Hours
Core Tip

Core tip: We present a case of esophageal carcinoma exclusively composed of adenocarcinoma simulating an esophageal gland duct. Morphologic and immunohistochemical examinations proved that adenocarcinomatous component here arose from the esophageal surface epithelium and showed a clear differentiation toward an esophageal gland duct. It is important to consider the possibility of this type of adenocarcinoma when diagnosing a ductal or glandular lesion of the esophagus in small biopsy specimens.