Copyright
©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jun 7, 2017; 23(21): 3765-3770
Published online Jun 7, 2017. doi: 10.3748/wjg.v23.i21.3765
Published online Jun 7, 2017. doi: 10.3748/wjg.v23.i21.3765
Role of surgery in pancreatic cancer
Trond A Buanes, Department of Hepato-Pancreatico-Biliary Surgery, Oslo University Hospital, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Pb 4956 N-0424 Oslo, Norway
Author contributions: Buanes TA solely contributed to the manuscript.
Conflict-of-interest statement: No potential conflicts of interest relevant to this article were reported.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Trond A Buanes, MD, PhD, Professor, Department of Hepato-Pancreatico-Biliary Surgery, Oslo University Hospital, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Nydalen, Pb 4956 N-0424 Oslo, Norway. trond.buanes@medisin.uio.no
Telephone: +47-23-070958 Fax: +47-23-072526
Received: January 26, 2017
Peer-review started: February 2, 2017
First decision: March 3, 2017
Revised: March 17, 2017
Accepted: April 21, 2017
Article in press: April 21, 2017
Published online: June 7, 2017
Processing time: 131 Days and 10 Hours
Peer-review started: February 2, 2017
First decision: March 3, 2017
Revised: March 17, 2017
Accepted: April 21, 2017
Article in press: April 21, 2017
Published online: June 7, 2017
Processing time: 131 Days and 10 Hours
Core Tip
Core tip: Both surgery and chemotherapy are mandatory in multimodal treatment of pancreatic cancer to obtain curative potential. The sequence of interventions is a core question: Upfront surgery or neoadjuvant chemotherapy with subsequent resection. Also the role of extended operations incorporating reconstruction of major mesenteric vessels and multivisceral resections is a matter of ongoing evaluation. The current direction of this development is increasing prognostic importance of surgical resection.