Prospective Study
Copyright ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. May 21, 2017; 23(19): 3556-3564
Published online May 21, 2017. doi: 10.3748/wjg.v23.i19.3556
Diagnosis of eosinophilic gastroenteritis is easily missed
Kodjo-Kunale Abassa, Xian-Yi Lin, Jie-Ying Xuan, Hao-Xiong Zhou, Yun-Wei Guo
Kodjo-Kunale Abassa, Xian-Yi Lin, Jie-Ying Xuan, Hao-Xiong Zhou, Yun-Wei Guo, Department of Gastroenterology, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, Guangdong Province, China
Author contributions: Abassa KK and Lin XY contributed equally to this work; Guo YW designed the study; Abassa KK, Lin XY, Xuan JY, Zhou HX and Guo YW performed the research; Abassa KK and Lin XY analyzed the data; Abassa KK and Guo YW wrote the paper.
Supported by Guangdong Science and Technology Program, No. 2016A020216012.
Institutional review board statement: The study was reviewed and approved by the Institutional Review Board of the Third Affiliated Hospital of Sun Yat-Sen University.
Clinical trial registration statement: This study is registered at Chinese Clinical Trial Registry (ChiCTR). The registration identification numbers are ChiCTR-ORD-16009004 for the retrospective study and ChiCTR-DOD-16009003 for the prospective study.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors have no conflict of interest to report.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Yun-Wei Guo, MD, PhD, Associate Professor, Department of Gastroenterology, the Third Affiliated Hospital of Sun Yat-Sen University, No. 600, Tianhe Road, Tianhe District, Guangzhou 510630, Guangdong Province, China.
Telephone: +86-20-85252156 Fax: +86-20-85253336
Received: January 22, 2017
Peer-review started: January 23, 2017
First decision: February 23, 2017
Revised: March 6, 2017
Accepted: April 12, 2017
Article in press: April 12, 2017
Published online: May 21, 2017
Core Tip

Core tip: Eosinophilic gastroenteritis (EGE) is a rare but easily missed disorder. In our study, the biopsy slides from the patients who underwent gastroscopy or colonoscopy were reevaluated. We found that a diagnosis of EGE might have been missed in 4.40% (7/159) patients who underwent gastroscopy and in 4.27% (9/211) who underwent colonoscopy. Finally, a prospective study was performed and showed that in patients with refractory upper gastrointestinal symptoms, 5.74% (7/122) of patients represent a missed diagnosis of EGE. Therefore, physicians should increase their alertness and improve communication with pathologist to reduce the rate of missed diagnosis of EGE.