Copyright
©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. May 14, 2017; 23(18): 3269-3278
Published online May 14, 2017. doi: 10.3748/wjg.v23.i18.3269
Published online May 14, 2017. doi: 10.3748/wjg.v23.i18.3269
Effects of sleeve gastrectomy plus trunk vagotomy compared with sleeve gastrectomy on glucose metabolism in diabetic rats
Teng Liu, Ming-Wei Zhong, Xin Huang, Yu-Gang Cheng, Ke-Xin Wang, Shao-Zhuang Liu, San-Yuan Hu, Department of General Surgery, Qilu Hospital of Shandong University, Jinan 250012, Shandong Province, China
Yi Liu, Health and Family Planning Commission of Shandong Provincial Medical Guidance Center, Jinan 250012, Shandong Province, China
Author contributions: Liu T, Liu SZ and Hu SY designed the study and wrote the manuscript; Liu T and Zhong MW instructed on the whole study and prepared the figures; Liu Y and Wang KX collected and analyzed the data; Liu T, Huang X and Cheng YG performed the operations and performed the observational study; Huang X and Cheng YG performed the molecular investigations; all authors have approved the final version to be published.
Supported by National Natural Science Foundation of China , No. 81471019 (to Hu SY) and No. 81300286 (to Liu SZ) ; Foundation for Outstanding Young Scientist in Shandong Province , No. BS2013YY031 (to Liu SZ) ; Science and Technology Development Program of Shandong Province , No. 2014GGE27485 (to Liu SZ) ; Specialized Research Fund for the Doctoral Program of Higher Education of China , No. 20130131120069 (to Liu SZ) .
Institutional review board statement: The study was reviewed and approved by the Institutional Review Board of Qilu Hospital of Shandong University, Jinan, China.
Institutional animal care and use committee statement: All procedures involving animals were reviewed and approved by the Ethics Committee on Animal Experiment of Shandong University Qilu Hospital (IACUC protocol number: DWLL-2015-014).
Conflict-of-interest statement: All authors have no conflict of interest related to the manuscript.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: San-Yuan Hu, Professor, Department of General Surgery, Qilu Hospital of Shandong University, No. 107, Wenhua Xi Road, Jinan 250012, Shandong Province, China. husanyuan1962@hotmail.com
Telephone: +86-531-82166351 Fax: +86-531-86920598
Received: January 20, 2017
Peer-review started: January 20, 2017
First decision: February 9, 2017
Revised: April 25, 2017
Accepted: May 4, 2017
Article in press: May 4, 2017
Published online: May 14, 2017
Processing time: 114 Days and 14.4 Hours
Peer-review started: January 20, 2017
First decision: February 9, 2017
Revised: April 25, 2017
Accepted: May 4, 2017
Article in press: May 4, 2017
Published online: May 14, 2017
Processing time: 114 Days and 14.4 Hours
Core Tip
Core tip: To investigate the effects of sleeve gastrectomy plus trunk vagotomy (SGTV) compared with sleeve gastrectomy (SG) in a diabetic rat model, SGTV, SG, TV and Sham operations were performed on diabetic rats. The result showed that SG and SGTV resulted in better glucose regulation, but SGTV did not result in a better improvement in diabetes than SG alone.