Chen YL, Mo XQ, Huang GR, Huang YQ, Xiao J, Zhao LJ, Wei HY, Liang Q. Gene polymorphisms of pathogenic Helicobacter pylori in patients with different types of gastrointestinal diseases. World J Gastroenterol 2016; 22(44): 9718-9726 [PMID: 27956795 DOI: 10.3748/wjg.v22.i44.9718]
Corresponding Author of This Article
Yan-Qiang Huang, Professor, Department of Medical Microbiology and Immunology, Youjiang Medical University for Nationalities, No. 98 Countryside Road, Baise 533000, Guangxi Zhuang Autonomous Region, China. hyq77615@163.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Yu-Li Chen, Xiao-Qiang Mo, Gan-Rong Huang, Yan-Qiang Huang, Juan Xiao, Li-Juan Zhao, Hong-Yu Wei, Qian Liang, Department of Medical Microbiology and Immunology, Youjiang Medical University for Nationalities, Baise 533000, Guangxi Zhuang Autonomous Region, China
Author contributions: Chen YL, Mo XQ and Huang GR contributed equally to this work; Xiao J performed the majority of the writing; Zhao LJ, Wei HY and Liang Q performed data acquisition; Huang YQ performed the design, analysis, modification and verification.
Supported byNational Natural Science Foundation of China, No. 31460023; Natural Science Foundation of Guangxi, No. 2014GXNSFAA118206; Guangxi Key Discipline Fund (Pathogenic Microbiology), No. [2013]16; and Key Laboratory Fund of Colleges and Universities in Guangxi, No. Gui Jiao Ke Yan [2014]6.
Conflict-of-interest statement: There is no conflict of interest associated with any of the senior author or other coauthors contributing their efforts in this manuscript.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Yan-Qiang Huang, Professor, Department of Medical Microbiology and Immunology, Youjiang Medical University for Nationalities, No. 98 Countryside Road, Baise 533000, Guangxi Zhuang Autonomous Region, China. hyq77615@163.com
Telephone: +86-776-2853272 Fax: +86-776-2853272
Received: June 8, 2016 Peer-review started: June 29, 2016 First decision: August 2, 2016 Revised: August 17, 2016 Accepted: September 6, 2016 Article in press: September 6, 2016 Published online: November 28, 2016 Processing time: 151 Days and 2.7 Hours
Core Tip
Core tip: Helicobacter pylori (H. pylori) is the causative agent of gastrointestinal diseases such as atrophic gastritis and peptic ulcers. Manifestations associated with chronic H. pylori infection vary considerably among distinct geographic regions and these differences have been attributed at least in part to polymorphisms of H. pylori genes, particularly those encoding virulence factors. There are several reviews for polymorphisms of H. pylori genes. However, this is the first review to report the relationship between genetic polymorphisms and diseases. Virulence genes of H. pylori can be categorized into three main classes. This helps to understand the gene polymorphisms of pathogenic H. pylori in patients with different types of gastrointestinal diseases.
