Prospective Study
Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Nov 21, 2016; 22(43): 9623-9630
Published online Nov 21, 2016. doi: 10.3748/wjg.v22.i43.9623
Outcomes of partial splenic embolization in patients with massive splenomegaly due to idiopathic portal hypertension
Omer Ozturk, Gonca Eldem, Bora Peynircioglu, Taylan Kav, Aysegul Görmez, Barbaros Erhan Cil, Ferhun Balkancı, Cenk Sokmensuer, Yusuf Bayraktar
Omer Ozturk, Taylan Kav, Yusuf Bayraktar, Department of Gastroenterology, Hacettepe University School of Medicine, 06100 Ankara, Turkey
Gonca Eldem, Barbaros Erhan Cil, Ferhun Balkancı, Bora Peynırcıoglu, Aysegül Görmez, Department of Radiology, Hacettepe University School of Medicine, 06100 Ankara, Turkey
Cenk Sokmensuer, Department of Pathology, Hacettepe University School of Medicine, 06100 Ankara, Turkey
Author contributions: Peynircioglu B and Bayraktar Y designed the study; Ozturk O and Kav T wrote the manuscript and performed the statistical analysis; Eldem G and Görmez A performed the embolization procedure; Sokmensuer C evaluated the pathology; Cil BE and Balkancı F revised the manuscript.
Institutional review board statement: All experiments were in compliance with the ethics of the Institutional Review Board of Hacettepe University Medical Center.
Informed consent statement: Oral informed consent was obtained from all patients before taking part in the questionnaire.
Conflict-of-interest statement: All authors declare no conflicts of interest.
Data sharing statement: All collected data are present within the core of the manuscript.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Omer Ozturk, MD, Department of Gastroenterology, Hacettepe University School of Medicine, 06100 Ankara, Turkey. omr58oztrk@hotmail.com
Telephone: +90-505-9487945
Received: May 6, 2016
Peer-review started: May 8, 2016
First decision: June 20, 2016
Revised: July 11, 2016
Accepted: July 31, 2016
Article in press: August 1, 2016
Published online: November 21, 2016
Processing time: 195 Days and 18.5 Hours
Core Tip

Core tip: Partial splenic embolization (PSE) for hypersplenism is a novel percutaneous interventional method, has emerged as an alternative to surgery and is a viable approach in high-risk and inoperable patients with portal hypertension. The current trial, which is the largest study in the current literature, confirmed the safety and efficacy of PSE in patients with idiopathic portal hypertension (IPH) regarding complications and morbidity. PSE could be offered to patients with massive splenomegaly due to IPH, with low and manageable complication rates, as this study has confirmed.