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Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Sep 7, 2016; 22(33): 7389-7401
Published online Sep 7, 2016. doi: 10.3748/wjg.v22.i33.7389
MicroRNA biomarkers predicting risk, initiation and progression of colorectal cancer
Kyungjin Lee, Lynnette R Ferguson
Kyungjin Lee, Medical Programme and Discipline of Nutrition and Dietetics and Auckland Cancer Society Research Centre, Faculty of Medical and Health Science, The University of Auckland, Private Bag 92019, Auckland, New Zealand
Lynnette R Ferguson, Discipline of Nutrition and Dietetics and Auckland Cancer Society Research Centre, Faculty of Medical and Health Science, The University of Auckland, Private Bag 92019, Auckland, New Zealand
Author contributions: Lee K and Ferguson LR contributed equally to this work; Lee K performed a critical literature search and wrote the initial drafts of the manuscript; Ferguson LR conceived of the study, mentored Lee K in literature searching and critical evaluation, wrote parts of the manuscript and assumed a major editing role.
Conflict-of-interest statement: The authors declare no conflict of interests.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Lynnette R Ferguson, Professor of Nutrition, Discipline of Nutrition and Dietetics and Auckland Cancer Society Research Centre, Faculty of Medical and Health Science, The University of Auckland, Private Bag 92019, Auckland, New Zealand. l.ferguson@auckland.ac.nz
Telephone: +64-9- 9236372 Fax: +64-9-3737502
Received: April 18, 2016
Peer-review started: April 19, 2016
First decision: May 12, 2016
Revised: June 10, 2016
Accepted: August 1, 2016
Article in press: August 1, 2016
Published online: September 7, 2016
Core Tip

Core tip: The requirements for colonoscopic technologies in order to detect early stages of colorectal cancer are being superseded by highly sensitive microRNA technologies using various body fluids. As well as providing early warnings of the disease, these also potentially provide a highly sensitive marker of dietary efficacy in disease prevention or slowing of disease progression.