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©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jul 28, 2016; 22(28): 6547-6558
Published online Jul 28, 2016. doi: 10.3748/wjg.v22.i28.6547
Published online Jul 28, 2016. doi: 10.3748/wjg.v22.i28.6547
Epidemiology of functional gastrointestinal disorders in infants and toddlers: A systematic review
Ana Paula Ferreira-Maia, Yuan-Pang Wang, Institute and Department of Psychiatry (LIM-23), University of São Paulo Medical School, São Paulo 01060-970, SP, Brazil
Alicia Matijasevich, Department of Preventive Medicine, University of São Paulo Medical School, São Paulo 01246-903, SP, Brazil
Author contributions: All authors equally contributed to this paper with conception and design of the study, literature review and analysis, drafting and critical revision and editing, and final approval of the final version.
Conflict-of-interest statement: No potential conflicts of interest. No financial support.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Yuan-Pang Wang, MD, PhD, Institute and Department of Psychiatry (LIM-23), University of São Paulo Medical School, R. Dr. Ovídio Pires de Campos, 785, São Paulo 01060-970, SP, Brazil. gnap_inbox@hotmail.com
Telephone: +55-11-26616976 Fax: +55-11-26616976
Received: March 29, 2016
Peer-review started: April 4, 2016
First decision: May 12, 2016
Revised: May 26, 2016
Accepted: June 28, 2016
Article in press: June 29, 2016
Published online: July 28, 2016
Processing time: 115 Days and 4.3 Hours
Peer-review started: April 4, 2016
First decision: May 12, 2016
Revised: May 26, 2016
Accepted: June 28, 2016
Article in press: June 29, 2016
Published online: July 28, 2016
Processing time: 115 Days and 4.3 Hours
Core Tip
Core tip: Epidemiological studies on functional gastrointestinal disorders in infants and toddlers provide variable prevalence rates in both pediatric outpatient and inpatient practice. A number of investigations and reviews have been conducted using Rome’s criteria for functional disorders to depict the magnitude of the problem, however, few investigations have reported meaningful results with adequate methodology. The current literature review suggested higher impact of pediatric feeding and defecation problems that affect very young children, respectively infant regurgitation and functional constipation.