Retrospective Study
Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jul 7, 2016; 22(25): 5780-5789
Published online Jul 7, 2016. doi: 10.3748/wjg.v22.i25.5780
Nationwide trends and predictors of inpatient mortality in 83884 transjugular intrahepatic portosystemic shunt
Edward Wolfgang Lee, Andrew Kuei, Sammy Saab, Ronald W Busuttil, Francisco Durazo, Steven-Huy Han, Mohamed M El-Kabany, Justin P McWilliams, Stephen T Kee
Edward Wolfgang Lee, Andrew Kuei, Justin P McWilliams, Stephen T Kee, Department of Radiology, Division of Interventional Radiology, Ronald Reagan Medical Center at UCLA, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, United States
Sammy Saab, Francisco Durazo, Steven-Huy Han, Mohamed M El-Kabany, Department of Medicine, Division of Hepatology, Pfleger Liver Institute, University of California at Los Angeles, Los Angeles, CA 90095, United States
Ronald W Busuttil, Dumont-UCLA Transplant Center, Pfleger Liver Institute, Division of Liver and Pancreas Transplantation, Department of Surgery, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, CA 90095, United States
Author contributions: Lee EW, Kuei A, Saab S, Busuttil RW, Durazo F, Han SH, El-Kabany MM, McWilliams JP and Kee ST equally contributed to this paper with conception and design of the study, literature review and analysis, drafting and critical revision and editing, and final approval of the final version.
Institutional review board statement: As this study used a national database with only deidentified patient and hospital data, this study meets the “Exempt” criteria by the Institutional Board Review.
Conflict-of-interest statement: No financial conflict-of-interest to disclose.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Edward W Lee, MD, PhD, Department of Radiology, Division of Interventional Radiology, Ronald Reagan Medical Center at UCLA, David Geffen School of Medicine at UCLA, 757 Westwood Plaza, Suite 2125, Los Angeles, CA 90095, United States. edwardlee@mednet.ucla.edu
Telephone: +1-310-2678771 Fax: +1-310-2061294
Received: March 14, 2016
Peer-review started: March 15, 2016
First decision: March 31, 2016
Revised: April 21, 2016
Accepted: May 4, 2016
Article in press: May 4, 2016
Published online: July 7, 2016
Processing time: 112 Days and 5.8 Hours
Core Tip

Core tip: This is the first large-scale, national trends data investigating in-patient death following transjugular intrahepatic portosystemic shunt (TIPS) using the National Inpatient Sample database from 1998 to 2012. Over 80000 TIPS related data have been investigated. Overall in-patient mortality has been down-trending over the past 15 years. A significant decrease of mortality occurred after 2005 with an introduction of covered stent graft for TIPS which improved the patient survival and TIPS outcomes. Specific patient ethnicity, location, transfer status, primary diagnosis and comorbidities correlate with increased odds of in-hospital death after TIPS.