Retrospective Cohort Study
Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jun 14, 2016; 22(22): 5237-5245
Published online Jun 14, 2016. doi: 10.3748/wjg.v22.i22.5237
Long-term outcomes and prognostic factors of patients with obstructive colorectal cancer: A multicenter retrospective cohort study
Ishibe Atsushi, Ota Mitsuyoshi, Yamaguchi Kazuya, Kaida Syuhei, Kamiya Noriyuki, Momiyama Masashi, Watanabe Akira, Sekizawa Kentaro, Kamimukai Nobuyuki, Sugimasa Natsuko, Watanabe Jun, Ichikawa Yasushi, Kunisaki Chikara, Endo Itaru
Ishibe Atsushi, Endo Itaru, Department of Gastroenterological Surgery, Graduate School of Medicine, Yokohama City University, Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan
Ota Mitsuyoshi, Watanabe Akira, Kunisaki Chikara, Department of Surgery, Gastroenterological Center, Yokohama City University, Urafune, Minami-ku, Yokohama 232-0024, Japan
Yamaguchi Kazuya, Department of Surgery, Yokohama City Hospital, Okazawa, Hodogaya-ku, Yokohama 240-8555, Japan
Kaida Syuhei, Watanabe Jun, Department of Surgery, Yokosuka Kyosai Hospital, Maigahamadori, Yokosuka 238-8558, Japan
Kamiya Noriyuki, Department of Surgery, Ito Municipal Hospital, Ito 414-0055, Japan
Momiyama Masashi, Department of Surgery, Fujisawa City Hospital, Fujisawa 251-8550, Japan
Sekizawa Kentaro, Department of Surgery, Yokosuka City Hospital, Nagasaka, Yokosuka 240-0195, Japan
Kamimukai Nobuyuki, Department of Surgery, Yokohama Hodogaya Central Hospital, Kamadai, Hodogaya-ku, Yokohama 240-8585, Japan
Sugimasa Natsuko, Department of Surgery, Saiseikai Yokohamashi Nanbu Hospital, Kounandai, Kounan-ku, Yokohama 234-0054, Japan
Ichikawa Yasushi, Department of Oncology, Graduate School of Medicine, Yokohama City University, Yokohama 236-0004, Japan
Author contributions: Ishibe A and Ota M contributed to study conception and design; Yamaguchi K, Kaida S, Kamiya N, Momiyama M, Watanabe A, Sekizawa K, Kamimukai N, Sugimasa N, Watanabe J and Watanabe K contributed to data acquisition; Ishibe A contributed to data analysis, interpretation, and writing of article; Ichikawa Y, Kunisaki C and Endo I contributed to editing, reviewing and final approval of article.
Institutional review board statement: This study was reviewed and approved by the institutional review board of Yokohama City University.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: There are no conflicts of interest to report.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Atsushi Ishibe, MD, PhD, Department of Gastroenterological Surgery, Graduate School of Medicine, Yokohama City University, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan. aishibe@yokohama-cu.ac.jp
Telephone: +81-45-7872650 Fax: +81-45-7879161
Received: February 11, 2016
Peer-review started: February 12, 2016
First decision: March 7, 2016
Revised: March 20, 2016
Accepted: April 7, 2016
Article in press: April 7, 2016
Published online: June 14, 2016
Processing time: 112 Days and 1.9 Hours
Core Tip

Core tip: Obstructive colorectal cancer (CRC) still have poor prognosis. However, the prognostic factor of obstructive CRC is unclear. The aim of this article is to clarify the long-term outcome and the risk factors for obstructive CRC at multiple institutions. The five-year disease free survival and cancer-specific survival were 50.6% and 80.3%, respectively. T4 tumor and R1 resection were independent prognostic factors for both recurrence and survival.