Copyright
©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Apr 21, 2016; 22(15): 3892-3906
Published online Apr 21, 2016. doi: 10.3748/wjg.v22.i15.3892
Published online Apr 21, 2016. doi: 10.3748/wjg.v22.i15.3892
New treatment options for alcoholic hepatitis
Saggere Muralikrishna Shasthry, Shiv Kumar Sarin, Department of Hepatology, Institute of Liver and Biliary Sciences, New Delhi 110070, India
Author contributions: Shasthry SM and Sarin SK analyzed the literature and wrote the manuscript.
Conflict-of-interest statement: The authors have no conflict of interest to report.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Shiv Kumar Sarin, MD, DM, Department of Hepatology, Institute of Liver and Biliary Sciences, D-1, VasantKunj, New Delhi 110070, India. shivsarin@gmail.com
Telephone: +91-11-46300000 Fax: +91-11-26123504
Received: January 27, 2016
Peer-review started: January 29, 2016
First decision: February 18, 2016
Revised: March 7, 2016
Accepted: March 18, 2016
Article in press: March 18, 2016
Published online: April 21, 2016
Peer-review started: January 29, 2016
First decision: February 18, 2016
Revised: March 7, 2016
Accepted: March 18, 2016
Article in press: March 18, 2016
Published online: April 21, 2016
Core Tip
Core tip: With better treatment options available for other liver diseases like viral hepatitis the proportion of alcoholic liver disease is on the rise. Alcoholic hepatitis is the most serious presentation of alcoholic liver disease with significant morbidity, mortality and health care burden. Treatment options in steroid non-responders and steroid ineligible patients of severe alcoholic hepatitis are limited. Newer treatment options for these patients are the need of the hour. The molecular and cellular targets have been discussed.