Retrospective Cohort Study
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Mar 7, 2015; 21(9): 2668-2676
Published online Mar 7, 2015. doi: 10.3748/wjg.v21.i9.2668
Absolute monocyte and lymphocyte count prognostic score for patients with gastric cancer
Wan Kyu Eo, Da Wun Jeong, Hye Jung Chang, Kyu Yeoun Won, Sung Il Choi, Se Hyun Kim, Sung Wook Chun, Young Lim Oh, Tae Hwa Lee, Young Ok Kim, Ki Hyung Kim, Yong Il Ji, Ari Kim, Heung Yeol Kim
Wan Kyu Eo, Da Wun Jeong, Hye Jung Chang, Department of Hematology/Medical Oncology, Kyung Hee University Hospital at Gangdong, Seoul 134727, South Korea
Kyu Yeoun Won, Department of Pathology, Kyung Hee University Hospital at Gangdong, Seoul 134727, South Korea
Sung Il Choi, Department of Surgery, Kyung Hee University Hospital at Gangdong, Seoul 134727, South Korea
Se Hyun Kim, Graduate School, Dankuk University, Yongin 448701, South Korea
Sung Wook Chun, Yong Il Ji, Department of Obstetrics and Gynecology, Inje University College of Medicine, Busan 612896, South Korea
Young Lim Oh, Tae Hwa Lee, Heung Yeol Kim, Department of Obstetrics and Gynecology, Kosin University College of Medicine, Busan 602702, South Korea
Young Ok Kim, Department of Pathology, Kosin University College of Medicine, Busan 602702, South Korea
Ki Hyung Kim, Department of Obstetrics and Gynecology, Pusan National University Hospital, Pusan National University School of Medicine, and Biomedical Research Institute and Pusan Cancer Center, Busan 602739, South Korea
Ari Kim, Department of Obstetrics and Gynecology, Institute of Wonkwang Medical Science, College of Medicine, Wonkwang University, Iksan 570749, South Korea
Author contributions: Kim A and Kim HY carried out a role as co-corresponding authors equally; Eo WK and Kim HY designed the research; Choi SI performed Patient Recruitment; Jeong DW and Chang HJ performed data collection; Won KY and Kim YO performed data interpretation as responsible pathologists; Oh YL, Lee TH, Kim KH, Ji YI and Kim A analyzed the data and reviewed manuscript; Kim SH performed statistical analysis; Eo WK and Chun SW wrote the paper.
Supported by Kyung Hee University in 2006, No. KHU-20061216.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Heung Yeol Kim, MD, PhD, Department of Obstetrics and Gynecology, Kosin University College of Medicine, 34, Amnam-dong, Seo-gu, Busan 602702, South Korea. hykyale@yahoo.com
Telephone: +82-51-9906226 Fax: +82-51-9903300
Received: August 19, 2014
Peer-review started: August 20, 2014
First decision: September 27, 2014
Revised: October 16, 2014
Accepted: December 5, 2014
Article in press: December 8, 2014
Published online: March 7, 2015
Processing time: 202 Days and 8.2 Hours
Core Tip

Core tip: Our findings suggest that the absolute monocyte count (AMC) and absolute lymphocyte count (ALC) prognostic score combined by AMC and ALC can predicts survival and identify gastric cancer patients with a poor overall survival, and this prognostic score is independent of age, pathologic stage, and various inflammatory markers.