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©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Feb 28, 2015; 21(8): 2497-2503
Published online Feb 28, 2015. doi: 10.3748/wjg.v21.i8.2497
Published online Feb 28, 2015. doi: 10.3748/wjg.v21.i8.2497
Optimal initiation of Helicobacter pylori eradication in patients with peptic ulcer bleeding
Hyuk Yoon, Dong Ho Lee, Eun Sun Jang, Jaihwan Kim, Cheol Min Shin, Young Soo Park, Jin-Hyeok Hwang, Jin-Wook Kim, Sook-Hayng Jeong, Nayoung Kim, Departments of Internal Medicine, Seoul National University Bundang Hospital, Gyeonggi-do 463-707, South Korea
Author contributions: Yoon H and Lee DH were responsible for conception, design of the study, analysis and interpretation of data, and wrote the manuscript; Jang ES, Kim J, Shin CM, Park YS, Hwang J, Kin J, Jeong S and Kim N critically revised the article for important intellectual content; all the authors reviewed and approved the final version to be published.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Dong Ho Lee, MD, Departments of Internal Medicine, Seoul National University Bundang Hospital, 300 Gumi-dong, Bundang-gu, Seongnam, Gyeonggi-do 463-707, South Korea. dhljohn@yahoo.co.kr
Telephone: +82-31-7877006 Fax: +82-31-7874051
Received: July 29, 2014
Peer-review started: July 31, 2014
First decision: August 15, 2014
Revised: September 1, 2014
Accepted: October 15, 2014
Article in press: October 15, 2014
Published online: February 28, 2015
Peer-review started: July 31, 2014
First decision: August 15, 2014
Revised: September 1, 2014
Accepted: October 15, 2014
Article in press: October 15, 2014
Published online: February 28, 2015
Core Tip
Core tip: This study aimed to determine the optimal time to initiate Helicobacter pylori (H. pylori) eradication in patients hospitalized with peptic ulcer bleeding. There was no significant difference in the H. pylori eradication rate between patients who received eradication therapy during hospitalization and those who commenced therapy as outpatients. However, because many patients who were discharged before H. pylori infection was confirmed lost the opportunity to begin eradication therapy, H. pylori infection should be confirmed and eradication therapy started in patients with peptic ulcer bleeding prior to discharge.