Baba K, Oshita A, Kohyama M, Inoue S, Kuroo Y, Yamaguchi T, Nakamura H, Sugiyama Y, Tazaki T, Sasaki M, Imamura Y, Daimaru Y, Ohdan H, Nakamitsu A. Successful treatment of conversion chemotherapy for initially unresectable synchronous colorectal liver metastasis. World J Gastroenterol 2015; 21(6): 1982-1988 [PMID: 25684967 DOI: 10.3748/wjg.v21.i6.1982]
Corresponding Author of This Article
Akihiko Oshita, MD, PhD, Department of Surgery, JA Hiroshima General Hospital, 1-3-3 Jigozen, Hatsuka-ichi, Hiroshima 738-8503, Japan. oshita-akihiko@umin.ac.jp
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Kenta Baba, Akihiko Oshita, Mohei Kohyama, Satoshi Inoue, Yuta Kuroo, Takuro Yamaguchi, Hiroyuki Nakamura, Yoichi Sugiyama, Tatsuya Tazaki, Masaru Sasaki, Yuji Imamura, Atsushi Nakamitsu, Department of Surgery, JA Hiroshima General Hospital, Hiroshima 738-8503, Japan
Akihiko Oshita, Hideki Ohdan, Department of Gastroenterological and Transplant Surgery, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8551, Japan
Yutaka Daimaru, Department of Pathology, JA Hiroshima General Hospital, Hiroshima 738-8503, Japan
Author contributions: The first two authors contributed equally to this work; Oshita A and Kohyama M designed the surgical strategy; Oshita A, Baba K, Kohyama M and Sasaki M performed the operation; Inoue S, Kuroo Y, Yamaguchi T, Nakamura H, Sugiyama Y, Tazaki T, Imamura Y and Nakamitsu A are members of the operating team; Daimaru Y evaluated the historical findings; Baba K and Oshita A wrote the paper; Ohdan H revised the manuscript.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Akihiko Oshita, MD, PhD, Department of Surgery, JA Hiroshima General Hospital, 1-3-3 Jigozen, Hatsuka-ichi, Hiroshima 738-8503, Japan. oshita-akihiko@umin.ac.jp
Telephone: +81-829-363111 Fax: +81-829-365573
Received: May 23, 2014 Peer-review started: May 26, 2014 First decision: June 18, 2014 Revised: July 3, 2014 Accepted: July 24, 2014 Article in press: July 25, 2014 Published online: February 14, 2015 Processing time: 264 Days and 17.6 Hours
Core Tip
Core tip: A 72-year-old woman with a sigmoid colon cancer and a synchronous colorectal liver metastasis (CRLM) was referred to our hospital. The metastatic lesion was diagnosed to be initially unresectable. After she had undergone laparoscopic sigmoidectomy for the original tumor, she consequently had 6 courses of modified 5-fluorouracil, leucovorin, and oxaliplatin plus cetuximab, resulting in conversion chemotherapy. Preoperative percutaneous transhepatic portal vein embolization was performed to secure the future remnant liver volume. Finally, a right hemihepatectomy was successfully performed. The postoperative course was uneventful. She had no recurrence for 18 mo. This multidisciplinary strategy could contribute in facilitating curative hepatic resection for initially unresectable CRLM.
