Prospective Study
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Feb 14, 2015; 21(6): 1932-1937
Published online Feb 14, 2015. doi: 10.3748/wjg.v21.i6.1932
Incidence and psychological-behavioral characteristics of refractory functional dyspepsia: A large, multi-center, prospective investigation from China
Shu-Man Jiang, Lin Jia, Xiao-Gai Lei, Ming Xu, Sheng-Bing Wang, Jing Liu, Min Song, Wei-Dong Li
Shu-Man Jiang, Lin Jia, Xiao-Gai Lei, Jing Liu, Min Song, Wei-Dong Li, Department of Gastroenterology, Guangzhou First People’s Hospital, Guangzhou Medical University, Guangzhou 510180, Guangdong Province, China
Shu-Man Jiang, Lin Jia, Jing Liu, Department of Gastroenterology, Guangzhou Nansha Central Hospital, Guangzhou 510180, Guangdong Province, China
Ming Xu, Department of Gastroenterology, Guangdong Province Second People’s Hospital, Guangzhou 510180, Guangdong Province, China
Sheng-Bing Wang, Department of Gastroenterology, Meizhou Municipal People’s Hospital, Guangzhou 510180, Guangdong Province, China
Author contributions: Jiang SM, Jia L and Lei XG designed the study; Lei XG, Xu M, Wang SB, Liu J and Song M performed the study; Jiang SM, Jia L and Li WD analyzed the data; Jiang SM and Jia L wrote the paper; Jiang SM and Jia L contributed to the work equally and should be regarded as co-first authors.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Lin Jia, MD, Professor, Department of Gastroenterology, Guangzhou First People’s Hospital, Guangzhou Medical University, 195 Dongfeng West Road, Guangzhou 510180, Guangdong Province, China. jialin@medmail.com.cn
Telephone: +86-20-81628809 Fax: +86-20-81628809
Received: August 12, 2014
Peer-review started: August 13, 2014
First decision: September 15, 2014
Revised: September 27, 2014
Accepted: October 20, 2014
Article in press: October 21, 2014
Published online: February 14, 2015
Processing time: 182 Days and 19.9 Hours
Core Tip

Core tip: Functional dyspepsia is the most common functional gastrointestinal disease. Refractory functional dyspepsia (RFD) even makes patients see a doctor repeatedly and aggravates their medical expenses. However, there is rare research concerning the psychological-behavioral characteristics of RFD patients until now. Thus we performed a large, multicenter investigation of RFD in China, and the findings may illustrate the importance of recognition and diagnosis of RFD, and provide a basis for clinical treatment and the relapse prevention of this condition.