Case Report
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Dec 28, 2015; 21(48): 13587-13592
Published online Dec 28, 2015. doi: 10.3748/wjg.v21.i48.13587
Novel endoscopic over-the-scope clip system
Elia Armellini, Stefano Francesco Crinò, Marco Orsello, Marco Ballarè, Roberto Tari, Silvia Saettone, Franco Montino, Pietro Occhipinti
Elia Armellini, Stefano Francesco Crinò, Marco Orsello, Marco Ballarè, Roberto Tari, Silvia Saettone, Franco Montino, Pietro Occhipinti, Gastroenterology Division, Azienda Ospedaliero Universitaria “Maggiore della Carità”, 28100 Novara, Italy
Author contributions: Armellini E and Crinò SF wrote the paper and contributed equally to the manuscript; Armellini E, Orsello M, Crinò SF and Occhipinti P performed the endoscopic procedures; Ballarè M, Tari R and Saettone S collected and alalysed the data; we are indebted to Montino F for editing the movie clips.
Institutional review board statement: This case report was exempt from the Institutional Review Board standards at Azienda Ospedaliero Universitaria “Maggiore della Carità” in Novara.
Informed consent statement: The patients involved in this study gave them written informed consent authorizing use and disclosure of them protected health information.
Conflict-of-interest statement: All the authors have no conflicts of interests to declare.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Elia Armellini, MD, Gastroenterology Division, Azienda Ospedaliero Universitaria “Maggiore della Carità”, Corso Mazzini 18, 28100 Novara, Italy. elia_armellini@hotmail.com
Telephone: +39-321-3733206 Fax: +39-321-3733345
Received: April 15, 2015
Peer-review started: April 16, 2015
First decision: June 19, 2015
Revised: June 25, 2015
Accepted: August 30, 2015
Article in press: August 31, 2015
Published online: December 28, 2015
Processing time: 253 Days and 10 Hours
Core Tip

Core tip: We report our experience with the novel over-the-scope Padlock Clip™, applied in five patients in the clinical settings of oesophageal fistulas and refractory gastrointestinal bleeding. The Padlock ClipTM has shown reliable closure of wall defects in a porcine survival study, although clinical usage remains limited. As yet, there are no published data regarding its application in the management of non-variceal gastrointestinal bleeding. We provide a comprehensive iconographic documentation and two videos showing its application. We also accurately describe the device and its release system, pointing out the differences with the well-known over-the-scope clip system.