Retrospective Study
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Dec 21, 2015; 21(47): 13316-13324
Published online Dec 21, 2015. doi: 10.3748/wjg.v21.i47.13316
Long-term outcomes after radical gastrectomy in gastric cancer patients with overt bleeding
Lei Wang, Xu-An Wang, Jia-Qi Hao, Li-Na Zhang, Mao-Lan Li, Xiang-Song Wu, Hao Weng, Wen-Jie Lv, Wen-Jie Zhang, Lei Chen, Hong-Gang Xiang, Jian-Hua Lu, Ying-Bin Liu, Ping Dong
Lei Wang, Xu-An Wang, Jia-Qi Hao, Mao-Lan Li, Xiang-Song Wu, Hao Weng, Wen-Jie Lv, Wen-Jie Zhang, Lei Chen, Hong-Gang Xiang, Jian-Hua Lu, Ying-Bin Liu, Ping Dong, Department of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China
Li-Na Zhang, Department of Biostatistics, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China
Author contributions: Wang L, Wang XA and Hao JQ contributed equally to this work; Wang L, Wang XA, Hao JQ, Liu YB and Dong P conceived this research and participated in research design, writing of the manuscript, performance of the research, data analysis and manuscript revision; Zhang LN, Li ML, Wu XS, Lv WJ, Weng H, Zhang WJ, Chen L, Xiang HG and Lu JH participated in research design, data analysis and manuscript revision; all authors approved the final manuscript.
Institutional review board statement: The study was reviewed and approved by the Ethics Committee of Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine.
Informed consent statement: Informed consent is given by patients preoperatively and registered in the electronic patient file. All included patients accepted the possibility to collect their patient data.
Conflict-of-interest statement: The authors declare no conflicts of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Ping Dong, MD, Associate Professor, Department of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, No. 1665 Kongjiang Road, Shanghai 200092, China. dongping1050@163.com
Telephone: +86-21-25076315 Fax: +86-21-65030840
Received: June 5, 2015
Peer-review started: June 8, 2015
First decision: August 26, 2015
Revised: August 31, 2015
Accepted: September 28, 2015
Article in press: September 30, 2015
Published online: December 21, 2015
Core Tip

Core tip: Data regarding the clinicopathological characteristics and long-term outcomes of gastric cancer patients presenting with overt bleeding (OB) are extremely limited. Our result showed that the prognosis of gastric cancer patients with OB was no worse than the prognosis of those without OB. In fact, upper gastric cancer patients with OB exhibited tumors at less advanced pathological stages and had a better prognosis than upper gastric cancer patients without OB. This provided a new insight into the intrinsic nature of gastric cancer with OB.