Editorial
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Dec 14, 2015; 21(46): 12989-12995
Published online Dec 14, 2015. doi: 10.3748/wjg.v21.i46.12989
Nonalcoholic fatty liver disease and hepatic cirrhosis: Comparison with viral hepatitis-associated steatosis
Yuki Haga, Tatsuo Kanda, Reina Sasaki, Masato Nakamura, Shingo Nakamoto, Osamu Yokosuka
Yuki Haga, Tatsuo Kanda, Reina Sasaki, Masato Nakamura, Shingo Nakamoto, Osamu Yokosuka, Department of Gastroenterology and Nephrology, Chiba University, Graduate School of Medicine, Chiba 260-8670, Japan
Shingo Nakamoto, Department of Molecular Virology, Chiba University, Graduate School of Medicine, Chiba 260-8670, Japan
Author contributions: Haga Y, Kanda T, Sasaki R, Nakamura M, Nakamoto S and Yokosuka O solely contributed to this paper.
Conflict-of-interest statement: All authors have no conflict of interest statement.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Tatsuo Kanda, MD, PhD, Associate Professor, Department of Gastroenterology and Nephrology, Chiba University, Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, Japan. kandat-cib@umin.ac.jp
Telephone: +81-43-2262086 Fax: +81-43-2262088
Received: July 16, 2015
Peer-review started: July 18, 2015
First decision: August 31, 2015
Revised: September 7, 2015
Accepted: October 17, 2015
Article in press: October 20, 2015
Published online: December 14, 2015
Processing time: 146 Days and 4 Hours
Core Tip

Core tip: Nonalcoholic fatty liver disease (NAFLD) including nonalcoholic steatohepatitis (NASH) is a common liver disease in United States, European and Asian countries. NAFLD and NASH are associated with metabolic syndrome including obesity, type 2 diabetes mellitus and/or dyslipidemia. Hepatitis C virus (HCV) infections are associated with hepatic steatosis, type 2 diabetes mellitus, insulin resistance and cardiovascular related diseases. In comparison with HCV, the association between hepatitis B virus and steatosis remains unclear. Further studies about the mechanism of hepatic steatosis in viral hepatitis are needed.