Dextran sulfate sodium-induced acute colitis impairs dermal lymphatic function in mice
Germaine D Agollah, Grace Wu, Sunkuk Kwon, Center for Molecular Imaging, The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center, Houston, TX 77030, United States
Germaine D Agollah, The University of Texas Graduate School of Biomedical Sciences at Houston, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, United States
Ho-Lan Peng, The University of Texas Health Science Center at Houston, School of Public Health, Houston, TX 77030, United States
Author contributions: Agollah GD, Wu G and Kwon S contributed to the acquisition and interpretation and statistical analysis of in vivo and ex vivo data; Peng HL performed statistical analysis; Kwon S designed and supervised the research; Agollah GD and Kwon S wrote the manuscript.
Supported by (in part) A pilot/feasibility grant from NIH/National Institute of Diabetes and Digestive and Kidney Disease, Center Grant P30 DK56338 (for Kwon S); the Schissler Foundation Fellowship for Translational Studies of Common Human Diseases (for Agollah GD).
Institutional review board statement: The study was reviewed and approved by University of Texas Health Science Center Institutional Review Board.
Institutional animal care and use committee statement: All animal experiments were reviewed and approved by University of Texas Health Science Center Institutional Animal Welfare Committee (AWC-14-0034).
Conflict-of-interest statement: The authors declared that they have no conflicts of interest to this work.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Sunkuk Kwon, PhD, Assistant Professor, Center for Molecular Imaging, The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center, 1825 Pressler Street, SRB 330F, Houston, TX 77030, United States. sunkuk.kwon@uth.tmc.edu
Telephone: +1-713-5003563 Fax: +1-713-5000319
Received: May 16, 2015
Peer-review started: May 20, 2015
First decision: June 19, 2015
Revised: July 10, 2015
Accepted: August 31, 2015
Article in press: August 31, 2015
Published online: December 7, 2015
