Şirli R, Sporea I, Popescu A, Dănilă M. Ultrasound-based elastography for the diagnosis of portal hypertension in cirrhotics. World J Gastroenterol 2015; 21(41): 11542-11551 [PMID: 26556985 DOI: 10.3748/wjg.v21.i41.11542]
Corresponding Author of This Article
Roxana Şirli, MD, PhD, Department of Gastroenterology and Hepatology, “Victor Babeş” University of Medicine and Pharmacy, 10, Iosif Bulbuca Bv., 300736 Timişoara, Romania. roxanasirli@gmail.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Topic Highlight
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Nov 7, 2015; 21(41): 11542-11551 Published online Nov 7, 2015. doi: 10.3748/wjg.v21.i41.11542
Ultrasound-based elastography for the diagnosis of portal hypertension in cirrhotics
Roxana Şirli, Ioan Sporea, Alina Popescu, Mirela Dănilă
Roxana Şirli, Ioan Sporea, Alina Popescu, Mirela Dănilă, Department of Gastroenterology and Hepatology, “Victor Babeş” University of Medicine and Pharmacy, 300736 Timişoara, Romania
Author contributions: Şirli R designed the research regarding the paper and wrote the manuscript; Şirli R, Sporea I, Popescu A and Dănilă M performed research; Sporea I, Popescu A and Dănilă M revised and completed the manuscript; all authors approved the final version of the manuscript.
Conflict-of-interest statement: None of the authors have any conflicts of interest regarding this paper.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Roxana Şirli, MD, PhD, Department of Gastroenterology and Hepatology, “Victor Babeş” University of Medicine and Pharmacy, 10, Iosif Bulbuca Bv., 300736 Timişoara, Romania. roxanasirli@gmail.com
Telephone: +40-723-537039 Fax: +40-256-488003
Received: April 28, 2015 Peer-review started: May 6, 2015 First decision: June 2, 2015 Revised: July 11, 2015 Accepted: August 31, 2015 Article in press: August 31, 2015 Published online: November 7, 2015 Processing time: 189 Days and 12.2 Hours
Core Tip
Core tip: Ultrasound-based elastographic methods are being used more and more for the non-invasive assessment of liver fibrosis, with very good accuracy in diagnosing cirrhosis. Transient elastography is a promising method for predicting portal hypertension in cirrhotics, but it cannot replace upper digestive endoscopy. The diagnostic accuracy of employing acoustic radiation force impulse elastography in the liver to predict portal hypertension is debatable. It may be significantly increased if spleen stiffness is assessed, whether alone or in combination with liver stiffness and other parameters. Two-dimensional shear-wave elastography, the ElastPQ technique and strain elastography all need to be evaluated as predictors of portal hypertension.
