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©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Aug 28, 2015; 21(32): 9648-9655
Published online Aug 28, 2015. doi: 10.3748/wjg.v21.i32.9648
Published online Aug 28, 2015. doi: 10.3748/wjg.v21.i32.9648
Liver reserve function assessment by acoustic radiation force impulse imaging
Xiao-Lan Sun, Department of Ultrasound in Medicine, Shanghai Shidong Hospital, Shanghai 200438, China
Li-Wei Liang, Department of Gastroenterology, Shanghai Shidong Hospital, Shanghai 200438, China
Hui Cao, Department of Ultrasound in Medicine, Shanghai Second Military Medical University Affiliated Changhai Hospital, Shanghai 200433, China
Qiong Men, Department of Oncology, Shanghai Shidong Hospital, Shanghai 200438, China
Ke-Zhu Hou, Department of Surgery, Shanghai Shidong Hospital, Shanghai 200438, China
Zhen Chen, Department of Pathology, Shanghai Shidong Hospital, Shanghai 200438, China
Ya-E Zhao, Department of Radiology, Shanghai Shidong Hospital, Shanghai 200438, China
Author contributions: Sun XL and Liang LW contributed equally to this work; Sun XL and Liang LW designed the research; Sun XL, Liang LW, Cao H, Men Q, Hou KZ, Chen Z and Zhao YE performed the research; Cao H, Men Q, Hou KZ, Chen Z and Zhao YE contributed new reagents/analytic tools; Sun XL and Liang LW analyzed the data; Sun XL, Liang LW and Cao H wrote the paper.
Clinical trial registration statement: This study is not registered at Clinical trial because all data are gained from an ultrasound system.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: We declare that there are no conflicts of interest to disclose.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Li-Wei Liang, BE, Department of Gastroenterology, Shanghai Shidong Hospital, No. 999, Shi Guang Road, Shanghai 200438, China. 1533516615@qq.com
Telephone: +86-21-2506636
Received: March 15, 2015
Peer-review started: March 15, 2015
First decision: April 13, 2015
Revised: May 28, 2015
Accepted: June 26, 2015
Article in press: June 26, 2015
Published online: August 28, 2015
Processing time: 166 Days and 6.9 Hours
Peer-review started: March 15, 2015
First decision: April 13, 2015
Revised: May 28, 2015
Accepted: June 26, 2015
Article in press: June 26, 2015
Published online: August 28, 2015
Processing time: 166 Days and 6.9 Hours
Core Tip
Core tip: Seventy-six patients with liver tumors were assessed by acoustic radiation force impulse (ARFI) imaging. We found that liver stiffness (LS) was positively correlated with Indocyanine green (ICG)-R15 and the Child-Pugh score, but was negatively correlated with ICG-K. Aspartate aminotransferase, aminotransferase and total bilirubin were positively correlated with LS, while albumin was negatively correlated with LS. The receiver-operator characteristic curve revealed that when LS value was 2.34 m/s, the Youden index was at its highest point. For patients with liver tumors, ARFI imaging is a useful tool to assess liver reserve function.