Retrospective Study
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Aug 14, 2015; 21(30): 9142-9149
Published online Aug 14, 2015. doi: 10.3748/wjg.v21.i30.9142
Full-thickness excision using transanal endoscopic microsurgery for treatment of rectal neuroendocrine tumors
Wei-Jie Chen, Nan Wu, Jiao-Lin Zhou, Guo-Le Lin, Hui-Zhong Qiu
Wei-Jie Chen, Nan Wu, Jiao-Lin Zhou, Guo-Le Lin, Hui-Zhong Qiu, Department of Surgery, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, China
Author contributions: Chen WJ and Wu N contributed equally to this work, performed the research and wrote the manuscript; Zhou JL analyzed the data; Lin GL and Qiu HZ designed and supervised the study; all authors have read and approved the final version to be published.
Institutional review board statement: The study was reviewed and approved by the Peking Union Medical College Hospital Review Board.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: No financial support or incentive has been provided for this manuscript. All authors have no conflicts of interest or financial ties to disclose.
Data sharing statement: We would share our technical appendix, statistical code, and dataset available from the corresponding author at [guolelin2002@163.com]. Participants gave informed consent for data.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Guo-Le Lin, MD, Department of Surgery, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Shuaifuyuan 1, Beijing 100730, China. linguole@126.com
Telephone: +86-10-69152621 Fax: +86-10-69156002
Received: February 25, 2015
Peer-review started: February 26, 2015
First decision: March 26, 2015
Revised: April 9, 2015
Accepted: May 7, 2015
Article in press: May 7, 2015
Published online: August 14, 2015
Core Tip

Core tip: Rectal neuroendocrine tumors increase quickly and steadily. Although transanal endoscopic microsurgery (TEM) was widely used for rectal neoplasms, the application of TEM in the full-thickness excision of rectal neuroendocrine tumors has not been well investigated. We analyzed data of all rectal neuroendocrine tumor patients who underwent local full-thickness excision using TEM as a primary excision or as complete surgery after incomplete resection by endoscopic polypectomy. The results suggested that full-thickness excision using TEM is a safe, minimally invasive procedure which could achieve complete resection, and might be a first surgical option for complete removal of higher rectal neuroendocrine tumors of less than 2 cm.