Wang DD, Xu Y, Zhu ZM, Tan XL, Tu YL, Han MM, Tan JW. Should temporary extracorporeal continuous portal diversion replace meso/porta-caval shunts in “small-for-size” syndrome in porcine hepatectomy? World J Gastroenterol 2015; 21(3): 888-896 [PMID: 25624722 DOI: 10.3748/wjg.v21.i3.888]
Corresponding Author of This Article
Jing-Wang Tan, MD, Department of Hepatobiliary Surgery, The First Affiliated Hospital of Chinese PLA General Hospital, 51 FuCheng Road, Haidian District, Beijing 100048, China. jingwangtan@126.com
Research Domain of This Article
Surgery
Article-Type of This Article
Basic Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Da-Dong Wang, Yong Xu, Zi-Man Zhu, Xiang-Long Tan, Yu-Liang Tu, Ming-Ming Han, Jing-Wang Tan, Department of Hepatobiliary Surgery, The First Affiliated Hospital of Chinese PLA General Hospital, Beijing 100048, China
Author contributions: Tan JW designed the research; Wang DD, Xu Y and Zhu ZM performed the research; Tan XL, Tu YL and Han MM analyzed the data; and Wang DD wrote the paper.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Jing-Wang Tan, MD, Department of Hepatobiliary Surgery, The First Affiliated Hospital of Chinese PLA General Hospital, 51 FuCheng Road, Haidian District, Beijing 100048, China. jingwangtan@126.com
Telephone: +86-10-66848633 Fax: +86-10-66848634
Received: April 4, 2014 Peer-review started: April 6, 2014 First decision: June 10, 2014 Revised: July 3, 2014 Accepted: September 5, 2014 Article in press: September 5, 2014 Published online: January 21, 2015 Processing time: 291 Days and 2.5 Hours
Core Tip
Core tip: Meso/porta-caval shunts have usually been adopted to relieve portal hyperperfusion in “small-for-size” syndrome (SFSS) or postoperative liver failure; however, these methods cannot dynamically adjust portal inflow to affect “functional competition”. In this study, extracorporeal continuous porta-caval diversion was temporarily adopted to relieve hyperperfusion, dynamically adjust the effect of portal inflow towards functional competition, and preserve optimal portal inflow. This also reduces injury to the sinusoidal endothelium, decreases endotoxin/bacterial translocation, and facilitates liver regeneration in SFSS after massive hepatectomy, and therefore could replace permanent meso/porta-caval shunts, which have no benefit or harm towards liver regeneration in late stages.
