Retrospective Study
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jul 14, 2015; 21(26): 8163-8169
Published online Jul 14, 2015. doi: 10.3748/wjg.v21.i26.8163
Management of hepatocellular carcinoma rupture in the caudate lobe
De-Fei Hong, Ying-Bin Liu, Shu-You Peng, Jin-Zhong Pang, Zhi-Fei Wang, Jian Cheng, Guo-Liang Shen, Yuan-Biao Zhang
De-Fei Hong, Shu-You Peng, Zhi-Fei Wang, Jian Cheng, Guo-Liang Shen, Yuan-Biao Zhang, Department of Hepatobiliary, Pancreatic Surgery and Minimally Invasive Surgery, Zhejiang Provincial People’s Hospital, Hangzhou 310014, Zhejiang Province, China
Ying-Bin Liu, Department of General Surgery, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China
Jin-Zhong Pang, Department of General Surgery, the First People’s Hospital of Qingdao Economic and Technical Department Zone, Qingdao 266555, Shandong Province, China
Author contributions: Hong DF, Liu YB and Peng SY designed the clinical study and surgical techniques; Pang JZ, Shen GL and Zhang YB participated in the management of the patients including working as the assistant in the operations; Cheng J did clinical data collection and analysis; Hong DF and Wang ZF wrote the paper.
Institutional review board statement: This work has been improved by the ethics committee of Zhejiang Provincial People’s Hospital.
Informed consent statement: Informed consent was obtained from all the patients at the admission to the hospital.
Conflict-of-interest statement: There is no conflict-of-interest in this clinical study.
Data sharing statement: No additional unpublished data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: De-Fei Hong, MD, FACS, Department of Hepatobiliary, Pancreatic Surgery and Minimally Invasive Surgery, Zhejiang Provincial People’s Hospital, 158 Shangtang Road, Hangzhou 310014, Zhejiang Province, China. hongdefi@163.com
Telephone: +86-571-85893957 Fax: +86-571-85893957
Received: December 31, 2014
Peer-review started: January 1, 2015
First decision: January 22, 2015
Revised: February 22, 2015
Accepted: April 28, 2015
Article in press: April 28, 2015
Published online: July 14, 2015
Processing time: 195 Days and 11.2 Hours
Core Tip

Core tip: Management of spontaneous rupture and hemorrhage of hepatocellular carcinoma is seldom reported due to its rareness and severity. This article demonstrates that caudate lobectomy is a valid treatment as well as the salvage choice for management in such cases based on our experience with the largest case series reported to date. Based on limited long-term follow-up data, overall 1-year and 3-year survival rates have been achieved. In addition, delayed surgery is advised over prudent resection until an experienced surgical team becomes available.