Meta-Analysis
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jul 7, 2015; 21(25): 7884-7894
Published online Jul 7, 2015. doi: 10.3748/wjg.v21.i25.7884
Diagnostic performance of magnifying narrow-band imaging for early gastric cancer: A meta-analysis
Ying-Ying Hu, Qing-Wu Lian, Zheng-Hua Lin, Jing Zhong, Meng Xue, Liang-Jing Wang
Ying-Ying Hu, Qing-Wu Lian, Jing Zhong, Meng Xue, Liang-Jing Wang, Department of Gastroenterology, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, Zhejiang Province, China
Ying-Ying Hu, Zheng-Hua Lin, Jing Zhong, Meng Xue, Liang-Jing Wang, Institute of Gastroenterology, Zhejiang University, Hangzhou 310016, Zhejiang Province, China
Qing-Wu Lian, Department of Gastroenterology, Lishui Central Hospital, Lishui 323000, Zhejiang Province, China
Zheng-Hua Lin, Department of Gastroenterology, Sir Runrun Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China
Author contributions: Wang LJ, Lian QW and Hu YY designed the research; Hu YY and Lin ZH performed the analysis and interpretation of the data; Hu YY wrote the manuscript; Wang LJ, Zhong J and Xue M reviewed the manuscript.
Supported by National Natural Science Foundation of China, No. 81302070 and No. 81372623; Zhejiang Provincial Natural Science Foundation of China, No. LY13H160019; and Zhejiang Province Key Science and Technology Innovation Team, No. 2013TD13.
Conflict-of-interest statement: The authors declare they have no conflict of interests.
Data sharing statement: Technical appendix, statistical code and dataset available from the corresponding author at wanglj76@hotmail.com. No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Liang-Jing Wang, MD, Department of Gastroenterology, the Second Affiliated Hospital, School of Medicine, Zhejiang University, No. 866 Yuhangtang Road, Hangzhou 310009, Zhejiang Province, China. wanglj76@hotmail.com
Telephone: +86-571-86006788 Fax: +86-571-86006788
Received: December 8, 2014
Peer-review started: December 9, 2014
First decision: January 22, 2015
Revised: February 2, 2015
Accepted: April 17, 2015
Article in press: April 17, 2015
Published online: July 7, 2015
Processing time: 211 Days and 19 Hours
Core Tip

Core tip: This is the first meta-analysis to systematically evaluate the diagnostic performance of magnifying endoscopy with narrow-band imaging (ME-NBI) for early gastric cancer (EGC) and the pooled results showed that ME-NBI was an effective endoscopic tool in EGC diagnosis, which has a better performance than conventional white-light imaging. Moreover, the morphology type of lesions, diagnostic standard and the size of lesions might influence the diagnostic value of ME-NBI.