Clinical Trials Study
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jun 28, 2015; 21(24): 7522-7528
Published online Jun 28, 2015. doi: 10.3748/wjg.v21.i24.7522
Use of magnetic resonance elastography for assessing liver functional reserve: A clinical study
Bin Li, Jie Min, Wei-Ren Liang, Guang-Qiang Zhang, Jian-Jun Wu, Kai Jin, Wei Huang, Cai-Yu Ying, Ming Chao
Bin Li, Jie Min, Wei-Ren Liang, Guang-Qiang Zhang, Jian-Jun Wu, Kai Jin, Wei Huang, Cai-Yu Ying, Ming Chao, Department of Radiology, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, Zhejiang Province, China
Author contributions: Chao M and Li B designed the research; Li B and Min J performed the research and wrote the manuscript; Liang WR, Zhang GQ, and Wu JJ performed the medical imaging reconstruction and data analysis; and Jin K, Huang W, and Ying CY provided technical support.
Supported by Health and Family Planning Commission of Zhejiang Province in China (partly).
Ethics approval: The study was reviewed and approved by the Human Research Ethics Committee of The Second Affiliated Hospital Zhejiang University School of Medicine.
Clinical trial registration: This study is registered at www.chictr.org.cn. The registration identification number is ChiCTR-DCD-15005799.
Informed consent: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest: The authors declare that they have no competing interests.
Data sharing: Technical appendix, statistical code, and dataset available from the corresponding author at doctor_chaoming@163.com.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Dr. Ming Chao, Department of Radiology, The Second Affiliated Hospital of Zhejiang University School of Medicine, No. 88 Jie fang Road, Hangzhou 310009, Zhejiang Province, China. doctor_chaoming@163.com
Telephone: +86-571-88767150 Fax: +86-571-87214631
Received: September 26, 2014
Peer-review started: September 29, 2014
First decision: December 2, 2014
Revised: November 14, 2014
Accepted: March 30, 2015
Article in press: March 31, 2015
Published online: June 28, 2015
Processing time: 276 Days and 7.3 Hours
Core Tip

Core tip: Liver functional determination is important for the preoperative evaluation of patients with hepatic carcinoma. We used magnetic resonance elastography to measure liver stiffness and then analyzed its correlation with the liver functional reserve test. The results showed that magnetic resonance elastography can be effectively used to assess liver functional reserve.