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©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jun 14, 2015; 21(22): 6794-6808
Published online Jun 14, 2015. doi: 10.3748/wjg.v21.i22.6794
Published online Jun 14, 2015. doi: 10.3748/wjg.v21.i22.6794
Prognostication and response assessment in liver and pancreatic tumors: The new imaging
Riccardo De Robertis, Emanuele Demozzi, Gino Puntel, Mirko D’Onofrio, Department of Radiology, Verona Comprehensive Cancer Network, G.B. Rossi Hospital, University of Verona, 37134 Verona, Italy
Paolo Tinazzi Martini, Department of Radiology, Casa di Cura Pederzoli, 37019 Peschiera del Garda, Italy
Silvia Ortolani, Sara Cingarlini, Giampaolo Tortora, Department of Oncology, Verona Comprehensive Cancer Network, G.B. Rossi Hospital, University of Verona, 37134 Verona, Italy
Andrea Ruzzenente, Alfredo Guglielmi, Department of Hepato-Biliary Surgery, Verona Comprehensive Cancer Network, G.B. Rossi Hospital, University of Verona, 37134 Verona, Italy
Claudio Bassi, Department of Pancreatic Surgery, Verona Comprehensive Cancer Network, G.B. Rossi Hospital, University of Verona, 37134 Verona, Italy
Paolo Pederzoli, Department of Pancreatic Surgery, Casa di Cura Pederzoli, 37019 Peschiera del Garda, Italy
Author contributions: All authors contributed equally to this work; Tinazzi Martini P, Ruzzenente A, Guglielmi A, Cingarlini S, Tortora G, Bassi C, Pederzoli P and D’Onofrio M designed the research; Demozzi E, Puntel G and Ortolani S performed the research and analyzed the data; and De Robertis R, Demozzi E and Puntel G wrote the paper.
Conflict-of-interest: The authors declare no potential conflict of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Riccardo De Robertis, MD, Department of Radiology, Verona Comprehensive Cancer Network, G.B. Rossi Hospital, University of Verona, Piazzale L.A. Scuro 10, 37134 Verona, Italy. riccardo.derobertis@hotmail.it
Telephone: +39-45-8124301 Fax: +39-45-8027490
Received: January 28, 2015
Peer-review started: January 28, 2015
First decision: March 10, 2015
Revised: March 25, 2015
Accepted: May 2, 2015
Article in press: May 4, 2015
Published online: June 14, 2015
Processing time: 141 Days and 14.5 Hours
Peer-review started: January 28, 2015
First decision: March 10, 2015
Revised: March 25, 2015
Accepted: May 2, 2015
Article in press: May 4, 2015
Published online: June 14, 2015
Processing time: 141 Days and 14.5 Hours
Core Tip
Core tip: Diffusion-weighted imaging and perfusion imaging could add functional information to the morphological evaluation of hepatic and pancreatic tumors. Diffusion-weighted imaging findings seem to be correlated with pathological features and could predict the clinical outcome of hepatocellular carcinomas and pancreatic tumors, especially neuroendocrine neoplasms. Apparent diffusion coefficient quantification and perfusion techniques can be of value for the evaluation of response to ablative treatments, loco-regional therapies and anti-angiogenic therapies, even at an early stage.