Huang W, Xiong JJ, Wan MH, Szatmary P, Bharucha S, Gomatos I, Nunes QM, Xia Q, Sutton R, Liu XB. Meta-analysis of subtotal stomach-preserving pancreaticoduodenectomy vs pylorus preserving pancreaticoduodenectomy. World J Gastroenterol 2015; 21(20): 6361-6373 [PMID: 26034372 DOI: 10.3748/wjg.v21.i20.6361]
Corresponding Author of This Article
Qing Xia, MD, Sichuan Provincial Pancreatitis Center, Department of Integrated Traditional Chinese Medicine and Western Medicine, West China Hospital, Sichuan University, Guo Xue Road 37, Chengdu 610041, Sichuan Province, China. xiaqing@medmail.com.cn
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Meta-Analysis
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. May 28, 2015; 21(20): 6361-6373 Published online May 28, 2015. doi: 10.3748/wjg.v21.i20.6361
Meta-analysis of subtotal stomach-preserving pancreaticoduodenectomy vs pylorus preserving pancreaticoduodenectomy
Wei Huang, Jun-Jie Xiong, Mei-Hua Wan, Peter Szatmary, Shameena Bharucha, Ilias Gomatos, Quentin M Nunes, Qing Xia, Robert Sutton, Xu-Bao Liu
Wei Huang, Mei-Hua Wan, Qing Xia, Sichuan Provincial Pancreatitis Center, Department of Integrated Traditional Chinese Medicine and Western Medicine, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
Jun-Jie Xiong, Xu-Bao Liu, Department of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
Peter Szatmary, Shameena Bharucha, Ilias Gomatos, Quentin M Nunes, Robert Sutton, NIHR Liverpool Pancreas Biomedical Research Unit, Royal Liverpool University Hospital, Liverpool L69 3BX, United Kingdom
Author contributions: Huang W and Xiong JJ contributed equally to this work; Liu XB, Sutton R and Xia Q designed the research, corrected and approved the final manuscript; Xiong JJ, Huang W, Wan MH, Szatmary P, Bharucha S, Gomatos I and Nunes QM developed the literature search and carried out the statistical analysis of studies; Xiong JJ, Huang W, Wan MH and Szatmary P carried out the extraction of data; Xiong JJ, Huang W, Wan MH and Szatmary P wrote the manuscript; all authors read and approved the final manuscript.
Supported by Research Special Fund for Public Welfare Industry of Health, No. 201202007; Science and Technology Support Program of Sichuan Province, No. 2013SZ0078; and National Institute for Health Research BRU Award.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Qing Xia, MD, Sichuan Provincial Pancreatitis Center, Department of Integrated Traditional Chinese Medicine and Western Medicine, West China Hospital, Sichuan University, Guo Xue Road 37, Chengdu 610041, Sichuan Province, China. xiaqing@medmail.com.cn
Telephone: +86-28-85422373 Fax: +86-28-85423373.
Received: September 3, 2014 Peer-review started: September 4, 2014 First decision: September 27, 2014 Revised: October 10, 2014 Accepted: December 1, 2014 Article in press: December 1, 2014 Published online: May 28, 2015 Processing time: 268 Days and 16.3 Hours
Core Tip
Core tip: As far as we know, pancreatoduodenectomy is one of the most complicated gastrointestinal operations and is associated with a number of serious postoperative complications. Modifications of standard operating techniques aim to reduce the incidence of complications and improve quality of life of patients while maintaining oncological effectiveness. Subtotal stomach-preserving pancreaticoduodenectomy (SSPPD) was specifically designed to reduce the incidence of delayed gastric emptying (DGE) and thus shorten recovery time in patients with pancreatic head and periampullary tumors. This study clarified that, compared to pylorus preserving pancreaticoduodenectomy (PPPD), SSPPD has a lower rate of DGE, shorter operation time and a shorter period of nasogastric intubation, albeit with no significant difference in pancreatic fistula and other postoperative complications. Therefore, SSPPD can improve intraoperative and short-term postoperative outcomes compared to PPPD for patients with pancreatic head and periampullary lesions.
