Copyright
©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. May 28, 2015; 21(20): 6304-6309
Published online May 28, 2015. doi: 10.3748/wjg.v21.i20.6304
Published online May 28, 2015. doi: 10.3748/wjg.v21.i20.6304
Sequential blood purification therapy for critical patients with hyperlipidemic severe acute pancreatitis
Hong-Liang Wang, Department of Critical Care Medicine, The Second Affiliated Hospital of Harbin Medical University, Harbin 150086, Heilongjiang Province, China
Kai-Jiang Yu, Department of Critical Care Medicine, The Third Affiliated Hospital of Harbin Medical University, Harbin 150081, Heilongjiang Province, China
Author contributions: Wang HL designed and performed the research, and wrote the paper; and Yu KJ analyzed the data.
Supported by Natural Science Foundation of Heilongjiang Province, China.
Ethics approval: The study was reviewed and approved by the Third Affiliated Hospital of Harbin Medical University Institutional Review Board.
Informed consent: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest: Wang HL has received fees for serving as a speaker.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Kai-Jiang Yu, MD, Department of Critical Care Medicine, The Third Affiliated Hospital of Harbin Medical University, No. 150 Haping Road, Harbin 150081, Heilongjiang Province, China. drkaijiang@163.com
Telephone: +86-451-6677580
Received: March 3, 2015
Peer-review started: March 3, 2015
First decision: March 10, 2015
Revised: March 24, 2015
Accepted: April 28, 2015
Article in press: April 28, 2015
Published online: May 28, 2015
Peer-review started: March 3, 2015
First decision: March 10, 2015
Revised: March 24, 2015
Accepted: April 28, 2015
Article in press: April 28, 2015
Published online: May 28, 2015
Core Tip
Core tip: Plasma exchange and continuous venous-venous hemofiltration have certain clinical effects in the treatment of hyperlipidemia acute severe pancreatitis, but there is currently no standardized combination therapy. Based on the 2012 Atlanta International Pancreatitis Consensus, we designed a sequential mode of combined application of plasma exchange and continuous venous-venous hemofiltration for the treatment of hyperlipidemia severe acute pancreatitis. This sequential blood purification therapy was found to be effective in the treatment of intensive care unit patients with hyperlipidemic severe acute pancreatitis and improved patient prognosis, and should therefore become the standardized treatment process.