Retrospective Study
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. May 7, 2015; 21(17): 5303-5310
Published online May 7, 2015. doi: 10.3748/wjg.v21.i17.5303
Prognostic significance of preoperative platelet count in patients with gallbladder cancer
Rui-Tao Wang, Ling-Qiang Zhang, Yi-Ping Mu, Jian-Bo Li, Xin-Sen Xu, Qing Pang, Lian-Kang Sun, Xing Zhang, Shun-Bin Dong, Lin Wang, Chang Liu
Rui-Tao Wang, Ling-Qiang Zhang, Xin-Sen Xu, Qing Pang, Lian-Kang Sun, Xing Zhang, Shun-Bin Dong, Lin Wang, Chang Liu, Department of Hepatobiliary Surgery, the First Affiliated Hospital of Xi’an Jiaotong University College of Medicine, Xi’an 710061, Shaanxi Province, China
Yi-Ping Mu, Department of Medical Record Information Office, the First Affiliated Hospital of Xi’an Jiaotong University College of Medicine, Xi’an 710061, Shaanxi Province, China
Jian-Bo Li, Department of Hepatobiliary Surgery, the West China Hospital of Sichuan University, Chengdu 610041, Sichuan Province, China
Author contributions: Wang RT and Zhang LQ contributed equally to this work; Wang RT and Liu C designed the research; Wang RT and Zhang LQ wrote the paper; Mu YP and Li JB collected the patient’s clinical data; Sun LK, Zhang X and Dong SB analyzed the data; Xu XS, Pang Q and Wang L revised the paper; all authors read and approved the final manuscript.
Supported by Hospital Foundation of the First Affiliated Hospital of Xi’an Jiaotong University College of Medicine (Xi’an, China), No. 2013YK36.
Ethics approval: The study was reviewed and approved by the First Affiliated Hospital of Xi’an Jiaotong University College of Medicine Institutional Review Board.
Informed consent: Informed written consent was provided by each participant or the participant’s legal guardian prior to enrollment in the study.
Conflict-of-interest: The authors have no conflicts of interest related to the manuscript.
Data sharing: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Chang Liu, MD, Department of Hepatobiliary Surgery, the First Affiliated Hospital of Xi’an Jiaotong University College of Medicine, No. 277 Yanta West Road, Xi’an 710061, Shaanxi Province, China. eyrechang@126.com
Telephone: +86-29-85323890 Fax: +86-29-85323890
Received: October 25, 2014
Peer-review started: October 28, 2014
First decision: November 14, 2014
Revised: December 5, 2014
Accepted: February 11, 2015
Article in press: February 11, 2015
Published online: May 7, 2015
Core Tip

Core tip: Platelet count (PLT) is implicated with a poor prognosis in many types of malignancies. Its prognostic value has not been reported in gallbladder carcinoma (GBC). The most important finding in this study was that PLT was correlated with GBC prognosis, and was an independent prognostic factor after surgery.