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©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Apr 21, 2015; 21(15): 4620-4626
Published online Apr 21, 2015. doi: 10.3748/wjg.v21.i15.4620
Published online Apr 21, 2015. doi: 10.3748/wjg.v21.i15.4620
Surgical procedure determination based on tumor-node-metastasis staging of gallbladder cancer
Xiao-Dong He, Jing-Jing Li, Wei Liu, Qiang Qu, Tao Hong, Xie-Qun Xu, Bing-Lu Li, Ying Wang, Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China
Hai-Tao Zhao, Department of Liver Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China
Author contributions: He XD and Li JJ contributed equally to this work; He XD and Zhao HT made substantial contributions to study conception and design; Li JJ, Liu W, Qu Q, Hong T, Xu XQ, Li BL and Wang Y participated in acquisition of data, analysis and drafting the article; and Zhao HT gave final approval of the version.
Supported by Capital Special Research Project for Health Development (2014-2-4012), State Natural Research Funding, No. 81372578; National Natural Science Foundation of China, No. 30970623 and No. 91229120; International Science and Technology Cooperation Projects, No. 2010DFA31840 and No. 2010DFB33720; and Program for New Century Excellent Talents in University, No. NCET-11-0288.
Informed consent: All study participants provided informed written consent prior to study enrollment.
Conflict-of-interest: We declare that we have no conflicts of interest.
Data sharing: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Hai-Tao Zhao, MD, Department of Liver Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 1 Shuaifuyuan, Wangfujing, Dongcheng District, Beijing 100730, China. zhaoht@pumch.cn
Telephone: +86-10-69156042 Fax: +86-10-69156043
Received: October 3, 2014
Peer-review started: October 4, 2014
First decision: October 29, 2014
Revised: November 11, 2014
Accepted: January 8, 2015
Article in press: January 8, 2015
Published online: April 21, 2015
Processing time: 198 Days and 17.2 Hours
Peer-review started: October 4, 2014
First decision: October 29, 2014
Revised: November 11, 2014
Accepted: January 8, 2015
Article in press: January 8, 2015
Published online: April 21, 2015
Processing time: 198 Days and 17.2 Hours
Core Tip
Core tip: Surgical resection is still the only cure for gallbladder cancer. Choice of surgery procedure based upon disease stages remains an important topic. This study showed that simple cholecystectomy would be the best choice for stages 0 and I gallbladder cancer (GBC) patients; stages II and III patients should actively seek for radical cholecystectomy (or extended radical resection surgery); and palliative treatment should be the major method for patients with stage IV GBC, and careful evaluation was necessary before applying any more aggressive surgical procedure.