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©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Apr 14, 2015; 21(14): 4302-4309
Published online Apr 14, 2015. doi: 10.3748/wjg.v21.i14.4302
Published online Apr 14, 2015. doi: 10.3748/wjg.v21.i14.4302
Anxiety and depression in patients with gastroesophageal reflux disease and their effect on quality of life
Xiao-Jun Yang, Hong-Mei Jiang, Xiao-Hua Hou, Jun Song, Division of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei Province, China
Xiao-Jun Yang, Department of Gastroenterology, Chongqing Hospital of Traditional Chinese Medicine, Chongqing 400037, China
Author contributions: Yang XJ wrote the paper; Jiang HM performed the research and collected the data; Yang XJ and Hou XH analyzed the data; Song J designed the research.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Jun Song, MD, Division of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1277 Jiefangdadao, Wuhan 430022, Hubei Province, China. song111jun@126.com
Telephone: 86-23-67953337 Fax: 86-27-85726930
Received: July 26, 2014
Peer-review started: July 31, 2014
First decision: August 15, 2014
Revised: October 26, 2014
Accepted: December 8, 2014
Article in press: December 8, 2014
Published online: April 14, 2015
Peer-review started: July 31, 2014
First decision: August 15, 2014
Revised: October 26, 2014
Accepted: December 8, 2014
Article in press: December 8, 2014
Published online: April 14, 2015
Core Tip
Core tip: In our study, the degree of anxiety and depression in non-erosive reflux disease (NERD) and reflux esophagitis patients was significantly higher than that of healthy controls, especially for the NERD group. The quality of life was negatively correlated with the degree of anxiety and depression.