Retrospective Study
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Apr 14, 2015; 21(14): 4248-4254
Published online Apr 14, 2015. doi: 10.3748/wjg.v21.i14.4248
Is cholecystectomy a reasonable treatment option for simple gallbladder polyps larger than 10 mm?
Hye Yon Park, Se Hoon Oh, Kwang Hyuck Lee, Jong Kyun Lee, Kyu Taek Lee
Hye Yon Park, Se Hoon Oh, Kwang Hyuck Lee, Jong Kyun Lee, Kyu Taek Lee, Division of Gastroenterology, Department of Internal Medicine, Samsung medical center, Sungkyunkwan University School of Medicine, Seoul 135-710, South Korea
Author contributions: Park HY performed research and wrote this paper; Oh SH collected data; Lee KH and Lee JK contributed data analysis; Lee KT designed this study and wrote this paper.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Kyu Taek Lee, MD, PhD, Professor, Division of Gastroenterology, Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710, South Korea. happymap@skku.edu
Telephone: +82-2-34103406 Fax: +82-2-34106983
Received: July 19, 2014
Peer-review started: July 22, 2014
First decision: August 27, 2014
Revised: September 22, 2014
Accepted: December 1, 2014
Article in press: December 1, 2014
Published online: April 14, 2015
Core Tip

Core tip: Gallbladder polyp (GBP) is a well-known pre-malignant lesion. The size of GBP, patient’s age and presence of symptoms are the risk factors for GB cancer. GBPs of 10 to 12 mm in diameter have lower risk of malignancy compared to that in GBPs larger than 13 mm, which is similar to the risk of malignancy in GBPs smaller than 10 mm. The use of this surgical indication (GBPs larger than 13 mm GBP) can prevent 50% of unnecessary cholecystectomies without the risk of missing malignant GBPs. Our findings suggest that GBPs with a diameter of 10 to 12 mm in patients younger than 45 years of age old can be observed carefully.