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©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Mar 14, 2015; 21(10): 3132-3138
Published online Mar 14, 2015. doi: 10.3748/wjg.v21.i10.3132
Published online Mar 14, 2015. doi: 10.3748/wjg.v21.i10.3132
Primary hepatic neuroendocrine tumor with multiple liver metastases: A case report with review of the literature
Kai Yang, Ying-Sheng Cheng, Department of Radiology and Medical Imaging, Shanghai Sixth People’s Hospital, Shanghai Jiaotong University, Shanghai 201306, China
Ji-Jin Yang, Xu Jiang, Ji-Xiang Guo, Department of Interventional Radiology, Affiliated ChangHai Hospital of Second Military Medical University, Shanghai 200433, China
Author contributions: Yang K analyzed the date and wrote the paper; Cheng YS track the paper; Yang JJ, Jiang X and Guo JX collected the data.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Ying-Sheng Cheng, MD, Professor, Chief, Department of Radiology and Medical Imaging, Shanghai Sixth People’s Hospital, Shanghai Jiaotong University, No. 600, Yi Shan Road, Shanghai 200433, China. chengyingsheng@hotmail.com
Telephone: +86-21-38297858 Fax: +86-21-38297706
Received: July 22, 2014
Peer-review started: July 24, 2014
First decision: September 15, 2014
Revised: October 26, 2014
Accepted: November 7, 2014
Article in press: November 11, 2014
Published online: March 14, 2015
Processing time: 236 Days and 21.4 Hours
Peer-review started: July 24, 2014
First decision: September 15, 2014
Revised: October 26, 2014
Accepted: November 7, 2014
Article in press: November 11, 2014
Published online: March 14, 2015
Processing time: 236 Days and 21.4 Hours
Core Tip
Core tip: Whereas more than 80% of the neuroendocrine tumors (NETs) found in the liver are metastatic, primary hepatic neuroendocrine tumors (PHNETs) are very rare, when a NET is found in the liver, it must be treated with great care to exclude metastasis from extrahepatic primary site, as that is a much more common occurrence. Only fewer than 100 cases of PHNETs have been reported in the English literatures and most was a case report. we report a case of PHNET with multiple liver metastases have focused on multiple imaging modalities, including computed tomography, magnetic resonance imaging, and digital subtraction angiography.