Meta-Analysis
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Mar 14, 2015; 21(10): 3085-3092
Published online Mar 14, 2015. doi: 10.3748/wjg.v21.i10.3085
Association between diabetes mellitus and gastroesophageal reflux disease: A meta-analysis
Xiao-Meng Sun, Jia-Cheng Tan, Ying Zhu, Lin Lin
Xiao-Meng Sun, Jia-Cheng Tan, Ying Zhu, Lin Lin, Department of Gastroenterology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, Jiangsu Province, China
Author contributions: Sun XM and Tan JC contributed equally to this work; Sun XM and Tan JC reviewed articles for inclusion and analyzed the data; Sun XM wrote the paper; Zhu Y performed the final consensus review and the final data analysis; Lin L designed the study, reviewed and revised the paper; and all authors approved the final version to be published.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Lin Lin, MD, PhD, Department of Gastroenterology, First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Rd, Gulou District, Nanjing 210029, Jiangsu Province, China. linlin9100@sina.cn
Telephone: +86-25-68136920 Fax: +86-25-83674636
Received: April 19, 2014
Peer-review started: April 19, 2014
First decision: May 29, 2014
Revised: June 21, 2014
Accepted: August 13, 2014
Article in press: August 28, 2014
Published online: March 14, 2015
Processing time: 331 Days and 0.9 Hours
Core Tip

Core tip: Based on a meta-analysis, we demonstrated that diabetes mellitus is associated with gastroesophageal reflux disease. Our findings suggested that this association was greater in patients aged < 50 years and in Asian populations.