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World J Gastroenterol. Mar 7, 2014; 20(9): 2392-2396
Published online Mar 7, 2014. doi: 10.3748/wjg.v20.i9.2392
Published online Mar 7, 2014. doi: 10.3748/wjg.v20.i9.2392
Serum 25-hydroxyvitamin D concentration and inflammatory bowel disease characteristics in Romania
Gabriela Dumitrescu, Catalina Mihai, Mihaela Dranga, Cristina Cijevschi Prelipcean, Department of Medical Sciences, Grigore T. Popa University of Medicine and Pharmacy, Iasi 700115, Romania
Author contributions: Dumitrescu G performed the majority of experiments, collected data, designed the study, wrote the manuscript, and provided financial support for this work; Mihai C, Dranga M and Prelipcean CC provided analytical tools and revised the manuscript for critical intellectual content.
Supported by A Grant from the Managing Authority of the Sectorial Operational Program for Human Resources Development, POSDRU 107/1.5/S/78702
Correspondence to: Gabriela Dumitrescu, PhD, Department of Medical Sciences, Grigore T. Popa University of Medicine and Pharmacy, 16 University Street, Iasi 700115, Romania. dumitrescu_gabriela@ymail.com
Telephone: +40-232-301600 Fax: +40-232-301640
Received: August 27, 2013
Revised: December 11, 2013
Accepted: January 3, 2014
Published online: March 7, 2014
Processing time: 191 Days and 10.9 Hours
Revised: December 11, 2013
Accepted: January 3, 2014
Published online: March 7, 2014
Processing time: 191 Days and 10.9 Hours
Core Tip
Core tip: This is the first prospective study assessing serum vitamin D levels in a Romanian population with inflammatory bowel disease. The results of the study highlight the low prevalence of sufficient vitamin D levels in patients with Crohn’s disease and ulcerative colitis. Furthermore, vitamin D levels were significantly lower in newly diagnosed cases, suggesting that disease treatment can help restore levels to some extent.