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World J Gastroenterol. Feb 28, 2014; 20(8): 2107-2112
Published online Feb 28, 2014. doi: 10.3748/wjg.v20.i8.2107
Published online Feb 28, 2014. doi: 10.3748/wjg.v20.i8.2107
3.0T 31P MR spectroscopy in assessment of response to antiviral therapy for chronic hepatitis C
Chun-Yu Zhang, Hai-Shan Yang, Department of Radiology, China-Japan Union Hospital Affiliated to Jilin University, Changchun 130033, Jilin Province, China
Qian Zhang, Department of Digestive Medicine, China-Japan Union Hospital Affiliated to Jilin University, Changchun 130033, Jilin Province, China
Hui-Mao Zhang, Department of Radiology, First Hospital Affiliated to Jilin University, Changchun 130033, Jilin Province, China
Author contributions: Zhang Q and Zhang CY contributed equally to this work; Yang HS contributed to the conception and design of this study; Zhang Q and Zhang CY collected, analyzed and interpreted the data, drafted the manuscript; and Zhang HM critically revised the content of the manuscript.
Correspondence to: Hai-Shan Yang, MD, Department of Radiology, China-Japan Union Hospital Affiliated to Jilin University, 126 Xiantai BLVD, Changchun 130033, Jilin Province, China. haishanyang@163.com
Telephone: +86-431-83995968 Fax: +86-431-84641986
Received: September 15, 2013
Revised: December 15, 2013
Accepted: January 3, 2014
Published online: February 28, 2014
Revised: December 15, 2013
Accepted: January 3, 2014
Published online: February 28, 2014
Core Tip
Core tip: This study assessed the value of 3.0T 31P magnetic resonance spectroscopy, a noninvasive technique, in testing response to antiviral therapy for chronic hepatitis C. The technique can provide biochemical information on hepatic metabolic processes. The phosphomonoester/phosphodiester ratio can be used as an indicator of response to antiviral treatment in chronic hepatitis C patients.