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World J Gastroenterol. Feb 14, 2014; 20(6): 1503-1509
Published online Feb 14, 2014. doi: 10.3748/wjg.v20.i6.1503
Published online Feb 14, 2014. doi: 10.3748/wjg.v20.i6.1503
Helicobacter pylori and gastric cancer: Indian enigma
Vatsala Misra, Department of Pathology, Moti Lal Nehru Medical College, Allahabad 211002, India
Renu Pandey, Pandey Research, 3312 Jackson Blvd, Rapid City, SC 57702, United States
Sri Prakash Misra, Manisha Dwivedi, Department of Gastroenterology and Hepatology MLN Medical College, Allahabad 211002, India
Author contributions: Misra V concept and design, analysis of data, manuscript preparation and final approval; Pandey R concept and design, collection and analysis of data, manuscript preparation; Misra SP and Dwivedi M collection of data, preparation of manuscript.
Correspondence to: Vatsala Misra, Professor, Department of Pathology, Moti Lal Nehru Medical College, Allahabad Lowther Road, Allahabad 211002, India. vatsala.m@rediffmail.com
Telephone: +91-941-5214308 Fax: +91-532-2256878
Received: October 6, 2013
Revised: November 12, 2013
Accepted: November 28, 2013
Published online: February 14, 2014
Processing time: 133 Days and 22.2 Hours
Revised: November 12, 2013
Accepted: November 28, 2013
Published online: February 14, 2014
Processing time: 133 Days and 22.2 Hours
Core Tip
Core tip: This review highlights the unusual finding of low prevalence of gastric cancer despite high prevalence of Helicobacter pylori in India and its probable causes including diet and genetic variations as seen in Indian patients. This finding is attributed to increased genetic resistance in addition to a vegetarian diet rich in antioxidants.