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World J Gastroenterol. Feb 14, 2014; 20(6): 1438-1449
Published online Feb 14, 2014. doi: 10.3748/wjg.v20.i6.1438
A review of Helicobacter pylori diagnosis, treatment, and methods to detect eradication
Elvira Garza-González, Guillermo Ignacio Perez-Perez, Héctor Jesús Maldonado-Garza, Francisco Javier Bosques-Padilla
Elvira Garza-González, Héctor Jesús Maldonado-Garza, Francisco Javier Bosques-Padilla, Servicio de Gastroenterología y Departamento de Patología Clínica, Hospital Universitario “Dr. José Eleuterio González” Universidad Autónoma de Nuevo León, Monterrey 64460, Mexico
Guillermo Ignacio Perez-Perez, Departments of Medicine and Microbiology, New York University School of Medicine, New York, NY 10010, United States
Author contributions: Garza-González E and Perez-Perez GI reviewed the diagnostic test of Helicobacter pylori infection; and Maldonado-Garza HJ and Bosques-Padilla FJ reviewed the treatment of Helicobacter pylori infection.
Correspondence to: Elvira Garza-González, PhD, Servicio de Gastroenterología y Departamento de Patología Clínica, Hospital Universitario “Dr. José Eleuterio González” Universidad Autónoma de Nuevo León, Av. Madero s/n, Colonia Mitras Centro, Edificio Barragán, segundo piso, Monterrey 64460, Mexico. elvira_garza_gzz@yahoo.com
Telephone: +52-81-83333664 Fax: +52-81-83333664
Received: September 27, 2013
Revised: November 15, 2013
Accepted: January 6, 2014
Published online: February 14, 2014
Processing time: 142 Days and 14.5 Hours
Core Tip

Core tip: This review focuses on diagnostic methods used to detect Helicobacter pylori (H. pylori) infection before and after eradication and on treatment regimens for H. pylori eradication. In this review, we emphasize the different regimens recommended in relation to differences in antibiotic resistance. Additionally, we review a test-and-treat strategy for and effective quadruple therapies, such as sequential, concomitant, and hybrid therapies. Furthermore, we review the use of probiotics as an additive to help increase H. pylori eradication rates.