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World J Gastroenterol. Dec 28, 2014; 20(48): 18413-18419
Published online Dec 28, 2014. doi: 10.3748/wjg.v20.i48.18413
Published online Dec 28, 2014. doi: 10.3748/wjg.v20.i48.18413
Efficacy of docetaxel combined with oxaliplatin and fluorouracil against stage III/IV gastric cancer
Yao-Jun Yu, Wei-Jian Sun, Ming-Dong Lu, Fei-Hai Wang, Dan-Si Qi, Yi Zhang, Pi-Hong Li, He Huang, Tao You, Zhi-Qiang Zheng, NO H09 Disease Dist., Department of General Surgery, the Second Affiliated Hospital of Wenzhou Medical University, Wenzhou 325003, Zhejiang Province, China
Author contributions: Yu YJ prepared the manuscript and supervised the research; Sun WJ collected the patients’ data; Lu MD made sample grouping and delivery; Wang FH performed preoperative data analysis and operation; Qi DS performed the pathological examination; Zhang Y contributed to the collection and comparison of influencing factors; Li PH performed the iconographical examination; Huang H made statistics of the patients’ data; You T performed the operation and sample grouping; and Zheng ZQ performed the operation and guided the research.
Correspondence to: Yao-Jun Yu, MD, NO H09 Disease Dist., Department of General Surgery, the Second Affiliated Hospital of Wenzhou Medical University, No. 109, Xueyuan Road, Wenzhou 325003, Zhejiang Province, China. yuyaojun26@163.com
Telephone: +86-577-88002709 Fax: +86-577-88002739
Received: March 8, 2014
Revised: September 15, 2014
Accepted: October 21, 2014
Published online: December 28, 2014
Revised: September 15, 2014
Accepted: October 21, 2014
Published online: December 28, 2014
Core Tip
Core tip: This study analysed the combination of docetaxel, oxaliplatin and fluorouracil in the neoadjuvant chemotherapy towards stage III/IV gastric cancer patients, and observed the changes of tumours after chemotherapy, as well as the surgical resection rate, postoperative pathological remission degree, clinical symptom remission degree and adverse reactions, aiming to verify the effectiveness and safety of this regimen in clinical applications.